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What Do I Need to Know About Pulsed Field Ablation?
Guest: Christopher DeSimone,
Host: Anthony Kashou, M.D.
In this episode of “ECG Making Waves, hosted by Dr. Anthony Kashou with guest Dr. Christopher DeSimone, the focus is on understanding the evolution of ablation technology, particularly why the field has shifted toward pulsed field ablation. The conversation explores the key differences between traditional thermal ablation methods and pulsed field ablation, highlighting mechanisms, safety profiles, and clinical advantages. Additionally, it provides insight into what patients and clinicians can expect on the day of an ablation procedure, as well as important considerations for post-procedure follow-up and recovery.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 28-January-2026
By Mayo Clinic4.5
3030 ratings
What Do I Need to Know About Pulsed Field Ablation?
Guest: Christopher DeSimone,
Host: Anthony Kashou, M.D.
In this episode of “ECG Making Waves, hosted by Dr. Anthony Kashou with guest Dr. Christopher DeSimone, the focus is on understanding the evolution of ablation technology, particularly why the field has shifted toward pulsed field ablation. The conversation explores the key differences between traditional thermal ablation methods and pulsed field ablation, highlighting mechanisms, safety profiles, and clinical advantages. Additionally, it provides insight into what patients and clinicians can expect on the day of an ablation procedure, as well as important considerations for post-procedure follow-up and recovery.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.
LinkedIn: Mayo Clinic Cardiovascular Services
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 28-January-2026

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