The Proof with Simon Hill

Why you should test ApoB | Dan Soffer, Md


Listen Later

Episode #339. Are you getting the full picture of your heart health? Learn why ApoB is the test you shouldn't skip. In this episode, I sit down with Dr Daniel Soffer, a preventive cardiologist and lipidologist, to break down the importance of ApoB testing for cardiovascular risk assessment.

You'll learn why ApoB provides more comprehensive insights than LDL cholesterol alone, who can benefit most from this test, and how it fits into preventive cardiology. Dr Soffer shares practical advice for assessing cardiovascular disease risk, discusses the implications of diet and genetics on heart health, and explores case studies to help you understand when and why ApoB testing is crucial.


Specifically, we discuss: 

  • Introduction (00:00)
  • Insight into Preventive Cardiology and Lipidology (01:38)
  • Understanding Lipoproteins and Their Role in Cardiovascular Disease (06:40)
  • Techniques for Lipoprotein Testing and Measurement (11:33)
  • Exploring Atherosclerosis and Lipoprotein Retention Hypothesis (31:18)
  • Epidemiological Changes in Health and Cardiovascular Profiles (55:06)
  • Concerns about the Keto Diet and Elevated ApoB Levels (58:26)
  • Approaches to Managing Elevated LDL Levels Clinically (01:01:13)
  • The Role of Evidence-Based Medicine in Cardiovascular Guidelines (01:07:15)
  • Comparing ApoB and LDL Cholesterol in Cardiovascular Risk (01:14:36)
  • Understanding Discordance in Lipid Measurements (01:18:36)
  • Advanced Imaging Techniques for Risk Assessment (01:25:50)
  • Guidelines and Considerations for Statin Therapy (01:44:30)
  • Coronary Artery Calcium Score, Stroke Risks, and Carotid Ultrasound (01:54:03)
  • Dietary Interventions and Carotid Intima-Media Thickness (IMT) (01:59:22)
  • Case Study: Family History’s Role in Cardiovascular Risk (02:05:05)
  • Overview of Statins, PCSK9 Inhibitors, and Other Lipid-Lowering Therapies (02:12:24)
  • Aspirin Therapy and Imaging in Cardiovascular Health (02:26:06)
  • Setting Treatment Thresholds Based on ApoB Levels (02:39:57)
  • Closing Thoughts on Cardiovascular Risk and ApoB (02:44:16)

  • This episode is brought to you by:

    38TERA

    Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.

    Eimele

    Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions.

    WHOOP

    Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.

    Momentous

    My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at at livemomentous.com.

    Pique Tea

    Pique’s Black Friday special is HERE. For a limited time, get a Chai tea FREE with your qualifying purchase at piquelife.com/simon. This is the only time you can get your hands on their Chai. Act fast; this limited-time offering is sure to sell out! The offer ends November 16th.

    Eight Sleep

    Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF to get up to $600 off your Pod 4 Ultra purchase when bundled at eightsleep.com/theproof. This is their highest offer of the year! Try it risk-free for 30 days, with worldwide shipping.

    Simon Hill, MSc, BSc (Hons)

    Creator of theproof.com and host of The Proof with Simon Hill

    Author of The Proof is in the Plants

    Watch the episodes on YouTube or listen on Apple/Spotify

    Connect with me on InstagramTwitter, and Facebook

    ...more
    View all episodesView all episodes
    Download on the App Store

    The Proof with Simon HillBy Live better for longer

    • 4.9
    • 4.9
    • 4.9
    • 4.9
    • 4.9

    4.9

    2,510 ratings


    More shows like The Proof with Simon Hill

    View all
    The Rich Roll Podcast by Rich Roll

    The Rich Roll Podcast

    11,917 Listeners

    Nutrition Facts with Dr. Greger by Michael Greger, M.D. FACLM

    Nutrition Facts with Dr. Greger

    3,470 Listeners

    The mindbodygreen Podcast by mindbodygreen

    The mindbodygreen Podcast

    2,048 Listeners

    The Exam Room by the Physicians Committee by Physicians Committee

    The Exam Room by the Physicians Committee

    3,407 Listeners

    The Doctor's Kitchen Podcast by Dr Rupy Aujla

    The Doctor's Kitchen Podcast

    602 Listeners

    Feel Better, Live More with Dr Rangan Chatterjee by Dr Rangan Chatterjee: GP & Author

    Feel Better, Live More with Dr Rangan Chatterjee

    4,000 Listeners

    The Genius Life by Max Lugavere

    The Genius Life

    4,932 Listeners

    Dhru Purohit Show by Dhru Purohit

    Dhru Purohit Show

    3,487 Listeners

    The Dr. Hyman Show by Dr. Mark Hyman

    The Dr. Hyman Show

    9,259 Listeners

    The Peter Attia Drive by Peter Attia, MD

    The Peter Attia Drive

    8,375 Listeners

    PLANTSTRONG Podcast by Rip Esselstyn

    PLANTSTRONG Podcast

    2,336 Listeners

    Huberman Lab by Scicomm Media

    Huberman Lab

    29,339 Listeners

    ZOE Science & Nutrition by ZOE

    ZOE Science & Nutrition

    2,156 Listeners

    The Dr. Gabrielle Lyon Show by Dr. Gabrielle Lyon

    The Dr. Gabrielle Lyon Show

    1,278 Listeners

    Your Brain On by Drs. Ayesha and Dean Sherzai

    Your Brain On

    326 Listeners