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In this episode of Hypertrophy: Past and Present, Jake and Chris revisit Joe Weider’s early 1940 full-body program before breaking down the central problem that all split routines face: supraspinal CNS fatigue.
Key topics include:
• How calcium-ion–related fatigue and inflammation create global CNS fatigue
• Why back-to-back training days reduce recruitment, even for unrelated muscles
• Why full-body AAA and AB formats avoid these issues
By Chris Beardsley and Jake Doleschal4.8
1717 ratings
In this episode of Hypertrophy: Past and Present, Jake and Chris revisit Joe Weider’s early 1940 full-body program before breaking down the central problem that all split routines face: supraspinal CNS fatigue.
Key topics include:
• How calcium-ion–related fatigue and inflammation create global CNS fatigue
• Why back-to-back training days reduce recruitment, even for unrelated muscles
• Why full-body AAA and AB formats avoid these issues

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