Claudia Hammond talks to Jacopo Annese, director of the San Diego brain observatory about his mission to create what he calls 'a Hubble space telescope for the brain'. He is recruiting people who will be willing to donate their brains to his laboratory. By interviewing them regularly to record their detailed life histories and interests and by doing psychological tests he aims to provide a brain archive for neuroscientists in the future. But what sort of links can be established between brain anatomy and personality and what sort of people are willing to donate their brains to his lab?

Producer: Pam Rutherford.