Perimenopause Simplified

106. GLP-1s in Perimenopause: What Most Providers Are Missing


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GLP-1 medications and peptides are everywhere right now - but the conversation around them has become loud, polarized, and often missing context.

In this episode, I share why I intentionally waited to talk about GLP-1s, how I think about them through a functional and midlife lens, and why tools like peptides or hormones can't replace foundational health work.

This is a grounded, non-shaming conversation for women who want clarity (not hype) when it comes to weight, metabolism, muscle, and long-term health after 40.

You'll learn:

  • What GLP-1s and peptides are - and why they've become so popular
  • Why I'm neither "for" nor "against" GLP-1s, especially in perimenopause
  • The real risks of rapid weight loss without protein and strength training
  • What women on GLP-1s need to prioritize: muscle, nutrition, gut health, and nervous system support
  • Why no medication or peptide replaces lifestyle, hormones, and metabolic context

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Perimenopause SimplifiedBy Claudia Petrilli

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