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What if the real turning point for women's health isn't menopause itself, but the decade before it? Long before the symptoms hit, your brain, bones, and heart are already changing, silently. You can train hard, eat clean, and still lose strength, bone density, and cognitive sharpness if you're not addressing the biology underneath it all.
In this episode of EXTEND, I'm joined by Dr. Vonda Wright, orthopedic surgeon, researcher, and author of Unbreakable, to talk about how women can take control of midlife long before the "change." We get into what actually happens when estradiol starts to fall, why bone is an active endocrine organ (not just structure), and how to measure what really predicts longevity: VO₂ max, grip strength, sit-to-stand, and bone quality.
We also discuss her FACE framework, flexibility, aerobic base, carrying load, and equilibrium, a smarter way to train for longevity that protects your brain, bones, and hormones.
Dr. Vonda Wright is a double board-certified orthopedic surgeon, researcher, and author of Unbreakable. She's a leading expert in active aging and musculoskeletal longevity, known for helping midlife women build strength, preserve bone health, and optimize performance through data-driven prevention.
What's Discussed:
(00:00) Why Women Need to Rethink Midlife Health (05:54) The Longevity Equation: Strength, Hormones, and Prevention (17:39) The Forgotten Organ Driving Women's Aging: Bone\ (28:44) How to Build Bone Quality (Not Just Density) (34:55) Training Smarter in Midlife: The FACE Protocol for Strength and Power (44:45) How to Find Real Fitness Inspiration Online, and Filter Out the Noise
Learn more about Dr. Shah:
Website: https://www.drshah.com/
Clinic: https://www.next-health.com/
Instagram:@darshanshahmd
Learn more about Dr. Vonda Wright:
Website: https://www.drvondawright.com/ Instagram: https://www.instagram.com/drvondawright
By Darshan Shah, MD4.8
114114 ratings
What if the real turning point for women's health isn't menopause itself, but the decade before it? Long before the symptoms hit, your brain, bones, and heart are already changing, silently. You can train hard, eat clean, and still lose strength, bone density, and cognitive sharpness if you're not addressing the biology underneath it all.
In this episode of EXTEND, I'm joined by Dr. Vonda Wright, orthopedic surgeon, researcher, and author of Unbreakable, to talk about how women can take control of midlife long before the "change." We get into what actually happens when estradiol starts to fall, why bone is an active endocrine organ (not just structure), and how to measure what really predicts longevity: VO₂ max, grip strength, sit-to-stand, and bone quality.
We also discuss her FACE framework, flexibility, aerobic base, carrying load, and equilibrium, a smarter way to train for longevity that protects your brain, bones, and hormones.
Dr. Vonda Wright is a double board-certified orthopedic surgeon, researcher, and author of Unbreakable. She's a leading expert in active aging and musculoskeletal longevity, known for helping midlife women build strength, preserve bone health, and optimize performance through data-driven prevention.
What's Discussed:
(00:00) Why Women Need to Rethink Midlife Health (05:54) The Longevity Equation: Strength, Hormones, and Prevention (17:39) The Forgotten Organ Driving Women's Aging: Bone\ (28:44) How to Build Bone Quality (Not Just Density) (34:55) Training Smarter in Midlife: The FACE Protocol for Strength and Power (44:45) How to Find Real Fitness Inspiration Online, and Filter Out the Noise
Learn more about Dr. Shah:
Website: https://www.drshah.com/
Clinic: https://www.next-health.com/
Instagram:@darshanshahmd
Learn more about Dr. Vonda Wright:
Website: https://www.drvondawright.com/ Instagram: https://www.instagram.com/drvondawright

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