In this episode, the host McCall McPherson concludes a three-part series on longevity with Dr. Matt Kaeberlein, CEO of Optispan Inc., affiliate professor at the University of Washington, and co-founder of the Dog Aging Project. Dr. Kaeberlein explains the difference between biological and chronological aging, emphasizing the role of genetics, lifestyle, and environmental factors. He discusses the challenges of measuring biological age and critiques direct-to-consumer biological age tests for their lack of reliability. The conversation also covers the impact of nutrition, caloric restriction, and supplements on aging, highlighting the importance of proactive health optimization over reactive disease treatment.

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