In the first episode of a three-part series on the key factors that limit healthspan, Dr. Erin Faules speaks with Wild Health CEO Dr. Carl Seger about two common but often under-addressed contributors: atherosclerosis and mental health disorders.

This episode includes discussion of:

• Why atherosclerosis often progresses silently, and why calcium scores may miss early disease
• The link between depression, chronic stress, and cardiovascular risk
• The clinical relevance of advanced screening tools like coronary CTA, LP(a), and AI-driven risk assessment
• Treatment advances including GLP-1 receptor agonists and psychedelic-assisted therapy

This is Part 1 of a 3-part series exploring the 7 most common blocks to healthspan. Over the next two weeks we will dive into atrophy, inflammation, metabolic dysfunction, neurodegenerative disease and cancer.