Are you struggling with anxiety, sleeplessness, and low libido in perimenopause—even after starting hormone therapy? You're doing everything right, but still feel wired, exhausted, and disconnected from pleasure. The missing piece might surprise you: it's your nervous system.

In this episode of Pleasure in the Pause, host Gabriela Espinosa reveals why balancing hormones alone isn't enough. Groundbreaking research from UC San Francisco shows that your nervous system is literally woven into your ovaries, directly influencing how you age, how you experience menopause symptoms, and how much pleasure you can access in your body. If you've felt like your body is betraying you in midlife, this conversation will change how you understand stress, hormones, and intimacy forever.

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Highlights from our discussion include:

• Your nervous system and hormones are in constant conversation. Declining estrogen makes your nervous system more reactive to stress, which is why you suddenly feel more anxious and on edge in perimenopause—it's biology, not "in your head."
• New research reveals your stress response is wired into your ovaries. Scientists at UC San Francisco discovered that sympathetic nerves (fight-or-flight) form dense networks in your ovaries and directly influence how they age. Chronic stress doesn't just affect your mood—it affects your ovarian health and longevity.
• Pleasure requires nervous system safety. When you're stuck in fight, flight, or freeze, your body can't access pleasure or intimacy. You need to feel safe in your body first before you can experience arousal, desire, and deep connection.
• You need both calm AND charge. The goal isn't to always be relaxed—you need sympathetic energy for desire and aliveness, and parasympathetic energy for rest and connection. True nervous system health is flexibility: moving fluidly between states.
• Simple practices make a profound difference. Grounding exercises like feeling your feet on the floor, humming to stimulate your vagus nerve, taking micro-pauses throughout the day, and naming your nervous system state can help you shift from survival mode to safety and pleasure.

Your nervous system isn't something to fix or control—it's something to befriend and partner with. It's your body's way of speaking to you, telling you when you need rest, movement, connection, or pleasure. This week, practice one simple tool: when you feel overwhelmed, pause and feel your feet on the ground. Notice the contact. Take three deep breaths. This small act tells your nervous system you're safe—and that's where healing and pleasure begin.

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The information shared on Pleasure in the Pause is for educational and informational purposes only and is not intended as medical advice. Always consult your healthcare provider before making any decisions about your health or treatment. The views expressed by guests are their own and do not necessarily reflect the views of the host or Pleasure in the Pause.