Dhru Purohit Show

A Deep Dive Into the Role That Insulin Plays in Weight Gain and Chronic Disease with Dr. Ben Bikman, Ph.D.


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This episode is brought to you by Rupa Health and ButcherBox


There are many conflicting viewpoints on what drives weight gain. Excess calories? High insulin levels? Unwavering hunger? Dhru has been on a quest for answers to learn exactly how to shift body composition to lose fat and build muscle. 


Today on The Dhru Purohit Podcast, Dhru welcomes Dr. Ben Bikman on the show to continue his summer weight loss. In this episode, Dhru and Dr. Bikman dive deep into insulin's critical role in weight gain, obesity, and cardiometabolic disease. 


Dr. Ben Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Dr. Bikman has a Doctor of Philosophy in bioenergetics and completed his postdoctoral fellowship in metabolic disorders with the Duke-National University of Singapore Medical School. He is the author of the book Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing prediabetes, improving brain function, shedding fat, and preventing diabetes.


In this episode, Dhru and Dr. Bikman dive into (audio version / Apple Subscriber version):

-The perfect formula for creating a sick society (1:46 /1:46)

-The most underrated blood test for metabolic health (6:12 / 6:12)

-Optimal fasting insulin reference ranges (11:51 / 9:47)

-The two primary factors that contribute to weight gain (17:10 / 14:45)

-Dhru’s weight-loss journey and its relationship to calories and insulin (29:23 / 27:00)

-Is it possible to gain weight on low-carb diets? (48:26 / 46:16)

-Dr. Bikman’s stance on the role of calories in weight loss (1:01:14 / 57:48)

-Dr. Bikman’s thoughts on using satiety as a metric for weight loss (1:17 / 1:14:33)

-The protein leverage hypothesis (1:26:22 / 1:24:35)

-Protein recommendations for optimal health and weight loss (1:30:49 / 1:28:20)

-The role of skeletal muscle in glycemic control and diabetes prevention (1:33:57 / 1:31:31)

-The link between resistance training, muscle mass, and insulin resistance (1:38:56 / 1:37:33)

-Dr. Bikman’s four pillars for eating a healthy diet (1:49:42 / 1:49:10)


Also mentioned in this episode:

-Why We Get Sick

-Instagram: @benbikmanphd

-Dr. Bikman’s meal replacement shake: gethlth.com


For more on Dr. Ben Bikman, follow him on Instagram @BenBikmanPhD, and through his websites bikmanlab.byu.edu and insuliniq.com.


Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.


Right now, new members of ButcherBox receive New York strip steaks for a year PLUS $20 off your first order. Go to butcherbox.com/DHRU to sign up and use code DHRU.


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Dhru Purohit ShowBy Dhru Purohit

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