Increased scientific data and various guidelines now support use of computed tomography coronary angiography (CTCA) in various clinical settings. However, a knowledge gap remains regarding its usefulness in patient care. In this interview, Ron Blankstein, MD; Allen J. Taylor MD, FACC; and Poonam Velagapudi MD, MS, discuss when noninvasive CTCA can be used instead of cardiac catheterization. For 20+ insider interviews like these every month with CME/MOC credit, subscribe to ACCEL at www.ACC.org/ACCEL.