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This episode delves into the fascinating world of botulinum toxin. We take a comprehensive journey through the mechanisms behind how botulinum toxin operates, exploring the fundamental principles of how nerves trigger muscle contractions, and how botulinum toxin works to interfere with that. We unravel the rich history of the medical discovery of botulinum toxin and its evolution into an FDA-approved product with various therapeutic and cosmetic applications. Listen in to hear about:
Join us as we explore not just the sanctioned uses of Botox, but also the intriguing off-label applications, including its surprising potential to address a whole host of symptoms.
Key moments in this episode are:
00:19 How botulinum toxin works
01:04 How a nerve causes a muscle to contract
02:02 Brand names for botulinum toxin
02:23 History of discovery of botulinum toxin for medical use
03:21 FDA categories of use for Botox
03:29 Therapeutic uses for Botox
04:43 FDA-approved cosmetic uses for Botox
05:01 Off-label cosmetic uses for Botox
05:54 Botox for treatment of depression
07:05 Botox for treatment of premature ejaculation
07:15 Botox to prevent abnormal heart rhythms
07:30 Botox for the treatment of very cold hands
08:05 Botox to prevent scarring after surgery for cleft lip
08:55 Botox for treatment of painful intercourse
09:34 Side effects from Botox injections
10:50 Botox migration
Learn more about Botox injections here: https://www.foundationsfl.com/botox
Here's the link to the cold hand clinic at University of Chicago: https://www.uchicagomedicine.org/conditions-services/plastic-reconstructive-surgery/cold-hands-syndrome/treatment
Step into the incredible world of estrogen in our latest podcast episode. We unpack staggering statistics, explore the historical perceptions surrounding menopause, and unravel the intricate changes in women's bodies as they transition through this natural phase. From the gradual decline in egg count to the hormonal shifts that mark this milestone, we delve into the nitty-gritty details of menopause, shedding light on its far-reaching impacts beyond just the cessation of menstrual cycles. Plus hear the surprising health benefits of estrogen in men as well. Learn about:
This episode is a holistic exploration of menopause, offering insights that go beyond the surface to empower understanding and discussions about this crucial life stage.
Key moments in this episode are:
00:25 Menopause statistics
01:01 Were women ever expected to enter menopause??
02:33 How women lose eggs as we age
03:54 What happens to menstrual cycles as we approach menopause
04:28 Hormone changes at menopause
06:26 Overlap of menopause symptoms as aging symptoms
06:49 Vasomotor symptoms
07:27 What happens to the heart without estrogen
10:27 What happens to our bones without estrogen
11:30 At what age women reach maximum bone mass
12:43 It's what happens after a bone fracture that is harmful
14:42 What happens to our brain without estrogen
15:36 Progestins reversing benefits of estrogen
16:36 What happens to the vagina and bladder without estrogen
19:07 What happens to men without estrogen, or with too much estrogen
Learn more about the benefits of hormone optimization in men and women here: https://www.foundationsfl.com/bioidentical-hormone-optimization
Here's the 2014 study showing lower cardiovascular risks in women using ERT vs those taking statins: erglind IA, Andersen M, Citarella A, Linder M, Sundström A, Kieler H. Hormone therapy and risk of cardiovascular outcomes and mortality in women treated with statins. Menopause. 2015 Apr;22(4):369-76. doi: 10.1097/GME.0000000000000345. PMID: 25335101; PMCID: PMC4470525.
Here's the 2012 study showing improved outcomes in women treated with HRT vs no treatment: Schierbeck LL, Rejnmark L, Tofteng CL, Stilgren L, Eiken P, Mosekilde L, Køber L, Jensen JE. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial. BMJ. 2012 Oct 9;345:e6409. doi: 10.1136/bmj.e6409. PMID: 23048011.
Here's the 2009 study stratifying men's cardiovascular risk based on their estradiol levels: Jankowska EA, Rozentryt P, Ponikowska B, Hartmann O, Kustrzycka-Kratochwil D, Reczuch K, Nowak J, Borodulin-Nadzieja L, Polonski L, Banasiak W, Poole-Wilson PA, Anker SD, Ponikowski P. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901. doi: 10.1001/jama.2009.639. PMID: 19436016.
And all the other studies I discussed are available as well; please message me to get the links!
By focusing on restoration rather than "rejuvenation", you can help to revive the vagina and vulva back to what they once were!
Key moments in this episode are:
00:12 What is vaginal rejuvenation
01:08 Changes that can occur to the vaginal and vulva
02:27 Symptoms associated with damage to pelvic floor
03:58 Bringing this issue to the forefront of discussion
04:44 What women are asking for with vaginal rejuvenation
06:26 Non-surgical treatments to improve labial appearance
07:39 Surgical options to alter labia
08:50 Who should you choose to perform a surgery
12:11 Radiofrequency alone as a treatment
13:32 Role of vaginal estrogen in rejuvenation
14:35 Types of vaginal lasers
16:57 Hybrid vaginal lasers
17:44 Surgical options to tighten vagina
20:30 Strengthening the pelvic floor muscles
Obesity has become a pressing issue in the United States, with a significant increase in its prevalence over the past few decades. This episode explores the factors contributing to weight gain, genetics that may predispose individuals to obesity, and the environment in which we live., highlighting the control we each have over our weight and the potential to modulate genetic influences. We also discuss the impact of obesity on various medical conditions such as heart disease, stroke, hypertension, and diabetes. Obesity needs to be understood as a chronic and relapsing medical condition, rather than solely a cosmetic concern. Listen in to learn more:
Gain insight to understand obesity's medical complexities to explore various interventions, empowering you to make an informed choice for healthier living and weight management.
Hormone replacement therapy (HRT) and breast cancer risk has long been overestimated. For too long, both patients and providers have overestimate the risk of hormone replacement therapy and undervalued its value. Despite the fear surrounding HRT and breast cancer, the actual risks are relatively low.
By debunking the fear surrounding hormones and breast cancer, the aim is to empower women to make informed decisions and seek guidance from hormone specialists.
Key moments in this episode are:
0:00 Intro and facts about breast cancer
1:05 Current screening guidelines for breast cancer
1:53 Looking at how the WHI study was set up
3:35 What the headlines about WHI said
3:59 Behind the headlines
5:23 WHI from a personal perspective
7:18 Understanding the numbers
8:37 Risks of oral estrogens
10:30 What was causing the breast cancer risk?
11:08 Benefits of taking HRT
12:10 Alternates to synthetic progestins
Check out Dr Jackson's blog on the WHI here:
https://www.foundationsfl.com/post/getting-rid-of-whi-once-and-for-all
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Instagram foundationskristinjacksonmd
Website www.foundationsfl.com
FB https://facebook.com/advancedurogynecology
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