February 21, 2025

Blocking Estrogen on TRT? Here’s Why It’s Ruining Your Results with Dave Lee

25 minutes

Dave Lee discusses the contentious topic of estrogen in men's TRT. He highlights the polarized views surrounding estrogen testing and aromatase inhibition, emphasizing the confusion it creates for patients and leads many men to chase an unrealistic “Goldilocks zone” of estrogen inhibition.

Key Takeaways:

Blocking estrogen is unnecessary and harmful. Many of the benefits of testosterone come from its natural conversion into estrogen and DHT. Inhibiting this process can lead to negative side effects.

The real problem isn’t estrogen—it’s inflammation and poor metabolic health. If men experience “estrogenic side effects,” it’s usually due to improper dosing or metabolic dysfunction, not an inherent issue with estrogen itself.

Testosterone dosing should prioritize stability. Weekly or biweekly injections create hormone fluctuations that cause side effects. Dave advocates for more frequent injections (at least three times per week) or using trans-scrotal testosterone cream, which provides a more stable and effective delivery method.

Excess body fat contributes to unwanted estrogenic effects. Men with higher body fat percentages will naturally convert more testosterone into estrogen. The solution isn’t blocking estrogen but losing fat through proper nutrition and exercise while optimizing TRT dosing.

Victory Men’s Health provides comprehensive hormone care. Clinics like Victory look beyond testosterone alone, addressing thyroid health, DHEA, pregnenolone, and insulin sensitivity for a more holistic approach to hormone optimization.

Dave emphasizes that TRT should be customized based on an individual’s health, lifestyle, and response to treatment. If you're struggling with side effects, the answer isn’t to suppress estrogen but to refine your protocol and address underlying health factors.

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Disclaimer: The Women Want Strong Men Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

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