BBC Inside Science

Boy gets New Skin, The York Gospels, Stephen Hawking's Thesis


Listen Later

Researchers in Italy and Germany have saved the life of a boy with a life threatening genetic skin disease, using a combination of stem cell and gene therapy. 7 year old Hassan had lost 60% of his protective epidermis because of the condition, junctional epidermolysis bullosa. The severe blistering and consequent bacterial infections put his life in imminent danger. In a final attempt to save him, the scientists took a small area of unblistered epidermis from his body, separated the constituent skin cells and then engineered them with a normal version of the gene that was malfunctioning in Hassan's body. Sheets of healthy epidermis of an area of about one square metre were then grown in culture, and then grafted onto 80% of his body. Hassan is now living a normal life, back at school, playing football. Lead researcher Michele de Luca describes the remarkable recovery and Fiona Watt, director of the Centre for Stem Cell and Regenerative Medicine at Kings College London, explains how the procedure worked.

Scientists at the University of York are investigating medieval livestock farming through the study of the 1,000 year old York Gospels manuscript: not by reading it but by extracting proteins and DNA from its animal skin parchment pages.

Inside Science listener and Middle Eastern archaeologist Melissa Sharp takes the programme to task for suggesting that anyone can now use publically available sonar and satellite data to search for shipwrecks and other archaeological sites. It opens up the world's ancient and not so ancient heritage to looters, she says.

Since the University of Cambridge made Stephen Hawkings 1966 PhD thesis free to view and download last month, more than a million people have at least looked at it. Adam Rutherford talks to cosmologist Andrew Pontzen, biologist Matthew Cobb and neuroscientist Sophie Scott about the record-breaking thesis and asks whose first research project they'd like to download.

Producer: Andrew Luck-Baker

...more
View all episodesView all episodes
Download on the App Store

BBC Inside ScienceBy BBC Radio 4

  • 4.4
  • 4.4
  • 4.4
  • 4.4
  • 4.4

4.4

285 ratings


More shows like BBC Inside Science

View all
Global News Podcast by BBC World Service

Global News Podcast

7,913 Listeners

Business Daily by BBC World Service

Business Daily

523 Listeners

More or Less by BBC Radio 4

More or Less

863 Listeners

Newshour by BBC World Service

Newshour

1,067 Listeners

World Business Report by BBC World Service

World Business Report

296 Listeners

In Our Time by BBC Radio 4

In Our Time

5,576 Listeners

The Documentary Podcast by BBC World Service

The Documentary Podcast

1,808 Listeners

In Our Time: Science by BBC Radio 4

In Our Time: Science

743 Listeners

Friday Night Comedy from BBC Radio 4 by BBC Radio 4

Friday Night Comedy from BBC Radio 4

2,113 Listeners

The Infinite Monkey Cage by BBC Radio 4

The Infinite Monkey Cage

1,952 Listeners

The Naked Scientists Podcast by The Naked Scientists

The Naked Scientists Podcast

599 Listeners

Discovery by BBC World Service

Discovery

965 Listeners

Science Weekly by The Guardian

Science Weekly

429 Listeners

Inside Health by BBC Radio 4

Inside Health

102 Listeners

Curious Cases by BBC Radio 4

Curious Cases

756 Listeners

The Inquiry by BBC World Service

The Inquiry

746 Listeners

The Life Scientific by BBC Radio 4

The Life Scientific

227 Listeners

Science In Action by BBC World Service

Science In Action

331 Listeners

Unexpected Elements by BBC World Service

Unexpected Elements

363 Listeners

CrowdScience by BBC World Service

CrowdScience

471 Listeners

Evil Genius with Russell Kane by BBC Sounds

Evil Genius with Russell Kane

346 Listeners

Have You Heard George's Podcast? by BBC Sounds

Have You Heard George's Podcast?

235 Listeners

Elis James and John Robins by Significant Productions

Elis James and John Robins

326 Listeners

You're Dead to Me by BBC Radio 4

You're Dead to Me

3,245 Listeners

The World, the Universe and Us by New Scientist

The World, the Universe and Us

116 Listeners

Sport's Strangest Crimes by BBC Radio 5 Live

Sport's Strangest Crimes

73 Listeners

Uncanny by BBC Radio 4

Uncanny

689 Listeners

Lady Killers with Lucy Worsley by BBC Radio 4

Lady Killers with Lucy Worsley

528 Listeners

Believe in Magic by BBC Studios

Believe in Magic

630 Listeners

The Global Story by BBC World Service

The Global Story

394 Listeners

Miss Me? by BBC Sounds

Miss Me?

239 Listeners

The History Podcast by BBC Radio 4

The History Podcast

54 Listeners

Rory Stewart: The Long History of... by BBC Radio 4

Rory Stewart: The Long History of...

80 Listeners

The History Bureau by BBC

The History Bureau

96 Listeners