Hump Day Hormones

Breaking the Box: Why the FDA Just Removed the Black-Box Warning on Hormone Therapy


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This week, we’re stepping out of our Head-to-Toe Menopause Series for something big — one of the most important updates in women’s health in more than two decades.
On November 10, 2025, the FDA officially removed the black-box warning from hormone therapy. If you’ve ever felt confused, scared, or dismissed when asking about HRT… this episode will feel like justice.
We break down:
• Why the black-box warning was added in 2002
• The huge misunderstandings from the original WHI study
• What current research actually shows about the safety and benefits of hormone therapy
• The difference between oral vs. transdermal hormones
• The truth about breast cancer risks
• Why starting HRT under age 60 or within 10 years of menopause matters
• How this change empowers women and clinicians moving forward
You’ll learn why this decision is long overdue, what it means for your health, and why it may finally open doors for women to get the relief they’ve been denied for far too long.
If you’ve felt unheard, unsupported, or scared away from hormone therapy — this episode is your green light to start the conversation again.
Resources Mentioned:
– FDA Fact Sheet (email us for a copy)
– Episode 33: “HRT After 65”
Listen on Apple Podcasts or Spotify — and share with a friend who needs to know the real story about hormones and menopause.
As always, nothing in this episode is medical advice. Talk with your provider about what’s best for you.
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Hump Day HormonesBy Dr. Jill Jennings & Kortney Spann, APRN

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