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"The epigenome resets completely and there's no sign of aging. It's kind of fascinating...I think that we might have a tuneup where we go and get rejuvenated." - Dr. Rhonda Patrick

Imagine a future where we could reset our biological clock, turning back aging at the cellular level. Dr. Rhonda Patrick takes us on a mind-blowing journey through cutting-edge longevity research, explaining how scientists have discovered ways to reprogram old cells into youthful ones with no signs of aging. She breaks down Nobel Prize-winning research on the Yamanaka factors—four special genes that can transform an 80-year-old skin cell into an embryonic stem cell, effectively erasing all signs of aging and allowing that cell to become any cell type in the body.

The conversation ventures into the exciting field of partial cellular reprogramming, where scientists are finding ways to rejuvenate cells without completely changing their identity. Dr. Patrick shares insights about groundbreaking work at Altos Labs, where top scientists like Dr. Steve Horvath (pioneer of epigenetic clocks that measure biological age) are tackling the hurdles that stand between us and potential age reversal. With the exponential growth in synthetic biology and gene engineering, Patrick believes we could be just a couple of decades away from treatments that might reverse our biological age by ten years or more.

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