a16z crypto show

Crypto's Killer App?


Listen Later

with @zcabrams @psneville @rhackett

In this episode, Robert Hackett sits down with Sean Neville, cofounder of Circle and co-creator of the USDC stablecoin, and Zach Abrams, founder of Bridge (now part of Stripe), for a deep dive into the real story behind stablecoins, finding product-market fit, and the future of payments infrastructure.

They explore the earliest days of USDC — when stablecoins were far from obvious and regulatory frameworks didn’t exist. Sean shares how his conviction in “money running at internet speed” helped shape a multibillion-dollar asset. Zach recounts Bridge’s pivot from NFTs to stablecoin infrastructure — and how his business has changed since joining Stripe.

Together, they break down:

  • Why stablecoins are having their moment now
  • What counts as product-market fit (and why founders rarely “feel” it)
  • The challenges of building crypto and AI products within heavily regulated environments
  • Why new base-layer chains like Arc, Tempo, and others may be needed
  • How decentralization, liquidity moats, and interoperability will define the next decade of blockchain adoption
  • What the future of programmable money and AI-driven financial workflows looks like

Whether you’re a founder, a crypto-curious builder, or someone trying to understand where global payments are headed, this conversation — originally recorded live at our recent a16z crypto Founders Summit — offers insights from two operators at the center of an industry-defining transformation.

Guests:
Sean Neville — Cofounder, Circle; CEO and cofounder, Catena
Zach Abrams — Founder and CEO, Bridge (acquired by Stripe)

Highlights:

01:26 — Origins of USDC

02:44 — Why stablecoins are having their moment now

04:14 — Circle’s early product experiments

06:19— Surviving crypto cycles

07:35 — Bridge: From NFT payments to stablecoins

08:58 — What product-market fit actually feels like

20:02 — Inevitability and the founder vs. employer mindset

20:58 — Why Bridge joined Stripe

26:18 — How AI changes company building

29:38 — What students should study now

30:27 — Why new payment chains (Tempo & Arc)?

35:55 — Decentralization as imperative

Follow a16z crypto on...

  • X: https://x.com/a16zcrypto
  • LinkedIn: https://www.linkedin.com/showcase/a16zcrypto/posts/
  • Spotify: https://open.spotify.com/show/7pMZvsNXEnb0CYcPiDQywE
  • Apple Podcasts: https://podcasts.apple.com/us/podcast/web3-with-a16z-crypto/id1622312549
  • Youtube: https://www.youtube.com/@a16zcrypto

📩 Subscribe for more industry reports, trend updates, news analysis, builder guides, and other resources: https://a16zcrypto.substack.com/subscribe/ 

🎙️ Like, subscribe, comment, share the show: https://a16zcrypto.com/posts/podcast/ 

***

As always, none of the following should be taken as investment, business, legal, or tax advice. Please see a16z.com/disclosures for more important information, including a link to a list of our investments.


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

...more
View all episodesView all episodes
Download on the App Store

a16z crypto showBy a16z crypto, Robert Hackett, Sonal Chokshi

  • 4.6
  • 4.6
  • 4.6
  • 4.6
  • 4.6

4.6

57 ratings


More shows like a16z crypto show

View all
This Week in Startups by Jason Calacanis

This Week in Startups

1,296 Listeners

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch by Harry Stebbings

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch

540 Listeners

The a16z Show by Andreessen Horowitz

The a16z Show

1,100 Listeners

Invest Like the Best with Patrick O'Shaughnessy by Colossus | Investing & Business Podcasts

Invest Like the Best with Patrick O'Shaughnessy

2,341 Listeners

Unchained by Laura Shin

Unchained

1,209 Listeners

Y Combinator Startup Podcast by Y Combinator

Y Combinator Startup Podcast

232 Listeners

CoinDesk Podcast Network by CoinDesk

CoinDesk Podcast Network

648 Listeners

The Breakdown by Blockworks

The Breakdown

742 Listeners

16 Minutes News by a16z by Andreessen Horowitz

16 Minutes News by a16z

105 Listeners

Bankless by Bankless

Bankless

1,048 Listeners

All-In with Chamath, Jason, Sacks & Friedberg by All-In Podcast, LLC

All-In with Chamath, Jason, Sacks & Friedberg

10,231 Listeners

Dwarkesh Podcast by Dwarkesh Patel

Dwarkesh Podcast

548 Listeners

Raising Health by Andreessen Horowitz, a16z Bio + Health

Raising Health

152 Listeners

a16z Live by Andreessen Horowitz

a16z Live

25 Listeners

Raoul Pal: The Journey Man by Real Vision Podcast Network

Raoul Pal: The Journey Man

130 Listeners

No Priors: Artificial Intelligence | Technology | Startups by Conviction

No Priors: Artificial Intelligence | Technology | Startups

138 Listeners

BG2Pod with Brad Gerstner and Bill Gurley by BG2Pod

BG2Pod with Brad Gerstner and Bill Gurley

458 Listeners

AI + a16z by a16z

AI + a16z

33 Listeners