We're kicking off our new season with a deep dive into one of neuroscience's most fascinating mysteries: sleep. This unconscious third of our lives isn't just about rest – it's absolutely critical for brain health, memory consolidation, and overall well-being. But here's where it gets intriguing: recent research suggests that increased napping as we age might be an early warning sign of Alzheimer's disease.

To unpack this complex relationship, we're thrilled to welcome back Erin Gibson, assistant professor of psychiatry at Stanford School of Medicine and Wu Tsai Neuro affiliate. 

We'll explore whether age-related sleep changes are potential contributors to brain degeneration or valuable early indicators of otherwise invisible brain disorders, possibly opening doors for early intervention.

We'll also learn about Gibson's research, supported by the Knight Initiative for Brain Resilience at Wu Tsai Neuro, which investigates how myelin—the insulation of our nerve cells—could be a key missing link in understanding the relationship between sleep and brain health.

Join us for an enlightening discussion that might just change how you think about your nightly slumber and its profound impact on long-term cognitive function. 

Mentioned on the Show

• Dopamine and serotonin work in opposition to shape learning
• Gibson Lab at Stanford University School of Medicine
• Surprising finding links sleep, brain insulation, and neurodegeneration | Knight Initiative
• Extended napping in seniors may signal dementia | UCSF

Related Episodes

• Respect your Biological Clock | Erin Gibson
• Why sleep keeps us young | Luis de Lecea
• Why new Alzheimer's drugs don't work | Mike Greicius

Get in touch
We want to hear from your neurons! Email us at at [email protected] if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.

Episode Credits

This episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker and research assistance by G Kumar. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the

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