Karl Sterling Podcast

Dr. Nathan Bryan: The Surprising Health Benefits of Nitric Oxide


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The Importance of Nitric Oxide

Nitric Oxide’s Critical Role
Dr. Bryan explained that nitric oxide (NO) is one of the most vital molecules in human physiology. Although it lasts less than a second in the body, it regulates essential processes:

  • Vasodilation: Enhancing blood flow to organs.
  • Reducing inflammation and oxidative stress: Key factors in chronic disease.
  • Supporting immune function: Preventing immune dysfunction, such as in autoimmune diseases.
  • A deficiency in nitric oxide is linked to almost every age-related chronic disease, including hypertension, diabetes, sexual dysfunction, and Alzheimer’s.

    Chronic Diseases: A Common Connection
    Dr. Bryan identified four hallmarks of chronic diseases:

    1. Reduced blood flow to organs and tissues.
    2. Chronic inflammation.
    3. Oxidative stress from free radical imbalance.
    4. Immune dysfunction, often leading to autoimmunity.
    5. Nitric oxide addresses all these issues, making it crucial for preventing and managing chronic diseases.

      Modern Challenges to NO Levels
      Dr. Bryan emphasized how modern diets and lifestyles contribute to nitric oxide deficiency:

      • Diet: The Standard American Diet (SAD) is nutritionally poor, with a 78% decline in vegetable nutrient density since the 1940s. Processed foods, herbicides, pesticides, and excess sugar further disrupt metabolic health and nitric oxide production.
      • Exercise: Regular movement, from moderate activity to high-intensity interval training (HIIT), is essential. Dr. Bryan practices a daily non-negotiable routine of 100 push-ups, 100 sit-ups, and stretching.
      • Oral Hygiene’s Role
        Antiseptic mouthwash and fluoride-containing toothpaste can harm nitric oxide production by killing beneficial oral bacteria. Dr. Bryan recommends fluoride-free toothpaste and avoiding antibacterial mouthwashes to preserve the oral microbiome. He also announced the January launch of Cardiosmile, a toothpaste designed to remineralize teeth and support nitric oxide levels.

        Cancer and Nitric Oxide
        Dr. Bryan described cancer as primarily a metabolic disease, not a genetic one, citing:

        • The Warburg Effect: Disrupted mitochondrial function leads to hypoxia and low pH, fostering cancer growth.
        • Environmental Factors: Solid tumors often stem from infections, while blood cancers are linked to mutagenic toxins like pesticides.
        • Addressing cancer metabolically involves improving mitochondrial function, oxygenating tumor environments, detoxifying the body, and restoring nitric oxide levels to inhibit tumor growth.

          Systemic Issues in Healthcare
          Dr. Bryan criticized modern medicine for prioritizing profits over patient outcomes, with medications often leading to additional diagnoses and treatments. He advocates for a proactive approach to health through diet, exercise, and avoiding harmful habits.

          Practical Tips for Optimizing Nitric Oxide
          Dr. Bryan shared actionable steps:

          • Use fluoride-free toothpaste and avoid antibacterial mouthwash.
          • Avoid antacids, which impair nitric oxide production.
          • Eat more green leafy vegetables.
          • Exercise daily, even briefly.
          • Cancer Prevention Strategies
            Clean eating, physical activity, and maintaining nitric oxide levels are key to reducing cancer risk.

            Upcoming Book: The Secret of Nitric Oxide
            Dr. Bryan announced his book’s January release, blending 25 years of research with practical strategies for optimizing nitric oxide and improving health.

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