Autoimmune diseases including rheumatoid arthritis, psoriasis, multiple sclerosis and ulcerative colitis are on the rise in Western countries; there are now 72 of them affecting every organ of the body. Dr. Angela Lucterhand, Director of Product and Program Marketing at Ortho Molecular Products, is an expert on natural therapies for autoimmunity. Why the uptick in these diseases in the modern industrialized countries? She outlines the role diet, stress, environmental toxicity, and gut health play in autoimmunity. Elimination of food precipitants is a key to recovery; so, too, is addressing “leaky gut” and restoring balance of the microbiome. Certain supplements address gut integrity, tamp down inflammation, and support the mitochondria. Dr. Lucterhand details a functional medicine roadmap for reversing autoimmunity.