A lawyer, public policy expert, and tech entrepreneur, Paola Santana is the founder and CEO of GLASS, a software ecosystem using artificial intelligence to power high-performing governments. Her work includes engaging with The White House, the United States Congress, the FAA, and NASA to enact regulatory frameworks for new transportation technologies, and developing public infrastructure projects in Latin America. Previously, she co-founded the autonomous drone pioneer Matternet. In this conversation with Stanford adjunct lecturer Ravi Belani, Santana traces her unique path into entrepreneurship and shares her passion for solving difficult systemic challenges.

Alongside his wife Crystal, Chris Sacca built Lowercase Capital into an extraordinarily successful VC firm, leveraging very early-stage investments in transformational technology companies like Twitter, Uber, Instagram, and Stripe. He retired in 2017, but came out of retirement to head up the science and investing team at Lowercarbon Capital, which is pursuing ambitious solutions to the climate crisis through innovation in energy, building materials, transportation, food, industrial chemicals, reforestation, and more. In this conversation with Stanford adjunct lecturer Ravi Belani, Sacca discusses how he found such success in early-stage investing, and explains why he thinks we’re entering a golden age of tech-driven climate solutions.

Payal Kadakia is the founder of ClassPass, the health and wellness app that ​​connects users to fitness classes and other health-positive experiences in 30 countries worldwide. Kadakia is also the founder and artistic director of The Sa Dance Company. Kadakia’s first book, LifePass: Drop Your Limits, Rise to Your Potential, is forthcoming in February 2022. In this conversation with Stanford adjunct lecturer Ravi Belani, she discusses reconciling her dual identities as a business leader and a dancer and her belief that we are our most successful when we bring our whole selves to work.

Jessica McKellar is the founder and CTO of Pilot, an accounting firm powered by software that has raised more than $160 million in venture capital funding. She also founded Zulip, a group collaboration tool that was acquired by Dropbox in 2014, and Ksplice, which was acquired by Oracle. In this conversation with Stanford adjunct lecturer Emily Ma, McKellar discusses her 15-year journey founding three startups with her co-founders, as well as her passion for creating opportunities for the previously incarcerated.

Josh Giegel is the co-founder of Virgin Hyperloop, a company dedicated to making hyperloop transportation a reality. Giegel founded the company in 2014, when hyperloop was an idea on a whiteboard in a garage. A little over two years later, Virgin Hyperloop built a full-scale prototype. Previously, at SpaceX, Giegel led the successful testing of six different rocket engines. He then shifted to leading research activities at Echogen Power Systems. In this conversation with Stanford adjunct lecturer Emily Ma, Giegel shares his entrepreneurial story and explains how his personal mission statement shaped each step of the journey.

Alexandr Wang is the founder and CEO of Scale AI. He founded Scale while at MIT at the age of 19, after recognizing that he could accelerate companies’ abilities to deploy AI by combining a machine learning-powered data labeling system with human insight to ensure that models are trained on high-quality, trusted datasets. In this conversation with Stanford adjunct lecturer Emily Ma, Wang discusses the essential role of high-quality data in building powerful, useful, and unbiased AI and machine learning systems.

Sara Menker is the founder and CEO of Gro Intelligence, which uses data, analytics, and forecasting models to inform companies involved in the agricultural supply chain and organizations impacted by climate change. Hans Tung is a managing partner at GGV Capital, focusing on early-stage investments across the global digital economy. In this conversation with Stanford adjunct lecturer Emily Ma, Menker and Tung discuss the skills, tactics and technologies needed to solve complex, systemic challenges.

James Joaquin is the co-founder and managing director of Obvious Ventures, leading the team’s investments focused on plant-forward approaches to food (like Beyond Meat), “good for you” consumer goods (like Olly), and companies at the forefront of how people find and do their best work (like Incredible Health). Joaquin has been working in venture capital since 2007. Prior to investing, he served as president and CEO of Xoom.com and president and CEO of Ofoto, and co-founded When.com. In this conversation with Stanford adjunct lecturer and STVP director of principled entrepreneurship Jack Fuchs, Joaquin discusses his commitment to “world positive investing” and his belief that many highly successful 21st century businesses will be devoted to solving the world’s biggest problems.

Juliet Anammah is the chairwoman of Jumia Nigeria and the Chief Sustainability Officer of Jumia Group, the largest e-commerce platform in Africa and the first African tech startup to be listed on the NYSE. She previously served as the CEO of Jumia Nigeria for more than 4 years, overseeing the growth and transition of Jumia Nigeria from online retail to a full digital ecosystem that included marketplace, logistics and payments services. In this conversation with Darius Teter, executive director of Stanford Seed, Anammah explores the challenges of building a marketplace business in Africa as well as the huge untapped potential of e-commerce on the continent.

Daphne Koller is the CEO and founder of insitro, a machine learning-enabled drug discovery company. Previously, she was a professor of computer science at Stanford University for 18 years, co-founder and co-CEO of Coursera, and the Chief Computing Officer of Calico, an Alphabet company in the healthcare space. She received the MacArthur Foundation Fellowship in 2004. In this conversation with Stanford adjunct lecturer Ravi Belani, Koller examines the key turning points in her diverse and innovative career, and speaks about how she searched for the opportunities that would have the greatest impact on the world.