Dr. Mitchell sits down with Dr. Ronald Hoffman, a longtime New York physician and the voice behind Intelligent Medicine, for a wide-ranging conversation about how integrative and functional medicine grew from a controversial idea into a mainstream movement. They look back at the early days when practicing outside the box came with real professional risk, and what it took to stay grounded in science while still exploring nutrition and lifestyle based approaches.

They also get practical about what’s being done well today, where functional medicine can turn into formula and groupthink, and how patients can look for truly well trained clinicians instead of flashy shortcuts. The conversation moves into supplements, longevity basics, and a measured take on peptides, including the difference between pharmaceutical and food derived peptides and why quality and evidence matter. They close on AI in medicine, why experience and trust still matter, and what helps people stay vital as they age.

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