Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Conor McCann from the Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK and Dr Anestis Tsakiridis from the School of Biosciences, The University of Sheffield, Sheffield, UK on the paper "Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue" published in paper copy in Gut in September 2024.