In this inaugural episode of the new podcast series produced by ACC's Interventional Member Section, Dr. Poonam Velagapudi is joined by featured guests Drs. Debabrata Dash and Thomas Cuisset to discuss the Highlights from EuroPCR 2025.

Explore key insights from the 4D-ACS trial, followed by a discussion on its practical impact in clinical settings. The discussants examine the FAITAVI trial, highlighting major findings and their influence on procedural decision-making. A recent meta-analysis is also reviewed, with commentary on how the collective evidence may shape real-world interventional strategies. Tune in for a dynamic exchange on cutting-edge trials and their implications for the cath lab.

Related References:

1. The FAITAVI trial: angiography versus physiology-guided PCI in patients undergoing TAVI – 12-month follow-up data (PCR Online). 2025. Available at: https://www.pcronline.com/News/PCR-Press-Releases/2025/EuroPCR-2025-The-FAITAVI-trial-angiography-versus-physiology-guided-PCI-in-patients-undergoing-TAVI-12-month-follow-up-data. Accessed 6/24/25.

1. Ribichini F, Pesarini G, Fabris T, et al. A randomised multicentre study of angiography- versus physiologyguided percutaneous coronary intervention in patients with coronary artery disease undergoing TAVI: design and rationale of the FAITAVI trial. EuroIntervention. 2024 Apr 15;20(8):e504-e510. doi: 10.4244/EIJ-D-23-00679.

1. Jang Y, Park SD, Lee JP, et al. One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial. EuroIntervention. 2025 May 21:EIJ-D-25-00331. doi: 10.4244/EIJ-D-25-00331.

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