The brain has billions of neurons interconnected by trillions of synapses. It is at these synapses where memories are made.

Ground-breaking research by Timothy Bliss, Graham Collingridge and Richard Morris has transformed our understanding of memory, and offered new insights into devastating effects of failing memory. This year they won the Brain Prize, the world's most valuable award in brain research. Claudia Hammond meets them in front of an audience at London's Royal Institution to discuss how memories are made.