You hit 38, and all of the sudden the same stuff isn’t working like it used to! So, what’s going on? Dr. Mariza tackles the science behind weight changes in midlife, and how to build metabolic resilience and insulin sensitivity as you age. We also talk through lab work and how to make changes based on your blood work and symptoms. Perimenopause doesn’t have to suck, and small shifts can completely change your life in the decades to come!

Timestamps:

[3:12] Interview with Dr. Mariza

[3:26] What was the moment you knew you were in perimenopause? 

[7:03] What is happening to our hormones mid-life?

[16:20] Where should women realistically start?

[19:33] Are you ok with getting baseline markers in a blood test or is there a better way? 

[30:48] Is it normal for testosterone to be low and decline as women are in their upper 30s?

[34:07] What is metabolic flexibility and how do you know if you actually have it?

[37:03] Is there really a thing as being “in balance” with your hormones?

[39:02] I’m curious about when the right time is to get on HRT - should I start it as a preventative measure or wait until I experience symptoms?

[40:44] What should you test or do when you’re doing everything right and still gaining weight? 

[47:16] How does blood glucose drive a change in fat storage and how can we improve that? 

[53:14] I am 41 and the same weight as last year but my middle is different - no change in diet or exercise, in fact I’m more disciplined than I’ve ever been. Help! 

[57:06] How do we combat burnout on all things “life” when there’s no choice but to keep going?

[1:04:34] Are you more sensitive to cortisol in mid-life and perimenopause and, if so, how?

Episode Links:

Visit Dr. Mariza's Website

Perimenopause Survival Guide

Lab tests to run:

Complete blood count

Comprehensive metabolic panel (should have fasting glucose included)

Vitamin D3 – Needs to be 50+

Fasting insulin - 5 or below

Fasting blood glucose - 85 ml or lower

Hemoglobin A1C

C-Reactive Protein (CRP): Under 1

Lipid panel: HDL above 50

Apo B Test - under 85

Uric acid

Hormones

Cortisol

Full testosterone panel

Full thyroid panel 

Estradiol 

Progesterone 

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