Melvyn Bragg and guests discuss the life cycle of stars. In his poem Bright Star John Keats wrote, "Bright Star, would I were steadfast as thou art". For Keats the stars were symbols of eternity- they were beautiful and ordered and unchanging - but modern astronomy tells a very different story. Stars, like everything else in the universe, are subject to change. They are born among vast swirls of gas and dust and they die in the stunning explosions we call supernovae. They create black holes and neutron stars and, in the very beginning of the universe, they forged the elements from which all life is made. But how do stars keep burning for millions of years, why do they self-destruct with such ferocity and what will happen to the universe when they all go out?With Paul Murdin, Senior Fellow at the Institute of Astronomy, Cambridge; Janna Levin, Advanced Fellow in Theoretical Physics in the Department of Applied Mathematics & Theoretical Physics at the University of Cambridge; Phil Charles, Professor of Astronomy at Southampton University.

Melvyn Bragg and guests explore the creative force of originality. How far is it to do with origins, how far with the combination of the discoveries of others, which were themselves based on the thoughts of others, into an ever-receding and replicating past? Is invention original? Is original important? Is tradition more interesting and the reworking of what is traditional of greater value than the search for idiosyncrasy? And did our notion of the original genius come as much out of a commercial imperative for individual copyright in the eighteenth century, as a romantic view of human nature which came in, perhaps not co-incidentally, at the same time? In 1800, in his preface to Lyrical Ballads, Wordsworth wrote "Every great and original writer, in proportion as he is great and original, must himself create the taste by which he is to be relished". But did the notion of originality begin with the Romantics in the 18th century, or has society always valued originality? Should we consider Shakespeare an innovator or a plagiarist?To what extent is originality about perception rather than conception and is originality a concept without meaning today?With John Deathridge, King Edward Professor of Music at King’s College London; Jonathan Rée, philosopher and author of Philosophical Tales; Professor Catherine Belsey, Chair of the Centre for Critical and Cultural Theory at Cardiff University

Melvyn Bragg and guests discuss redemption. In St Paul's letter to the Galatians, he wrote: "Christ has set us free; stand fast therefore, and do not submit again to a yoke of slavery". This conception of Redemption as freedom from bondage is crucial for Judeo-Christian thought. In Christianity, the liberation is from original sin, a transformation from the Fall to salvation - not just for mankind but for individual human beings. The content of that journey is moral, gaining redemption by becoming better.So why is the idea of transformation so appealing to human beings? To what extent were Christian views of Redemption borrowed from Judaism? How did philosophers such as Marx reinterpret the concept of Redemption and can redemption retain its value in a world without God? Does its continuing power signify a deep psychological need in humankind?With Richard Harries, Bishop of Oxford; Janet Soskice, Reader in Modern Theology and Philosophical Theology at Cambridge University; Stephen Mulhall, Fellow and Tutor in Philosophy at Oxford University.

Melvyn Bragg and guests discuss meteorology. The Book of Genesis resounds with a terrible act of vengeance, carried out by an angry God seeking to punish his people. And the mechanism with which this is carried out - a catastrophic flood which wipes out evil on earth. In fact, many ancient civilisations believed extreme meteorological phenomena like thunder and lightning, hailstones and even meteors were acts of divine intervention. Running parallel with this belief, however, was also a desire to understand and explain the natural world through rational enquiry and observation. This complex relationship – between the natural world and divinity – has fascinated philosophers, artists and scientists alike from antiquity to our own time. Aristotle, for example, coined the phrase meteorology but to what extent did he link meteorological events to the cosmos and the Gods? How did the development of instrumentation during the Renaissance aid the prediction of weather events? Why did 18th century writers such as Keats feel that these scientific advances stripped the skies of its mystique and romance? And why does meteorology continue to fascinate and mystify to this day? With Vladimir Jankovic, Wellcome Research Lecturer at the Centre for the History of Science, Technology and Medicine at Manchester University;Richard Hamblyn, writer; Liba Taub, Director of the Whipple Museum of the History of Science at Cambridge University.

Melvyn Bragg and guests discuss the Aztec Empire. According to legend, the origins of it lie on a mythical island called Aztlan - "place of the white herons" - in the north of Mexico. From there this nomadic group of Mesoamericans are said to have undertaken a pilgrimage south to the fertile valleys of Central America. In the space of just 200 years, they formed what has been called the largest, and arguably the most ruthless, pre-Hispanic empire in North America which, at its zenith, was to rule over approximately 500 small states, comprising by the 16th century some 6 million people. Was it military might and intimidation alone that helped the Aztecs extend their power? What part did their complex belief system play in their imperial reach? Their use of human sacrifice has been well documented, but how widespread actually was it? How easily were the Spanish conquistadors able to Christianise this empire? And what legacy did the Aztecs leave behind that lives on in our world today?With Alan Knight, Professor of the History of Latin America at Oxford University and author of Mexico: From the Beginning to the Spanish Conquest; Adrian Locke, co-curator of the Aztecs exhibition at the Royal Academy of Arts; Elizabeth Graham, Senior Lecturer in Mesoamerican Archaeology at University College London.

Melvyn Bragg and guests discuss the Lindisfarne Gospels. In 597 Pope Gregory the Great ordered that a mission of monks be sent from Rome to convert Britain to its own brand of Christianity - lest it be submerged by the pagan beliefs of the Anglo-Saxon overlords. Just over 100 years later, the Lindisfarne Gospels were produced - lavish and ornate manuscripts, central to the story of how Britain came to be unified by the flag of the Roman Church – and they came to embody a set of beliefs and ideas that dominated Britain for a thousand years. Was the Rome mission in the 6th century the only strand of Christianity to sweep through Britain? Why did Northumbria become a key battleground for ideological dispute? How successful were the Lindisfarne Gospels in unifying the different strands of Christianity? To what extent did they serve as a founding statement of Christian identity in Britain?With Dr Michelle Brown, Curator of Illuminated Manuscripts at the British Library and author of A Guide to Western Historical Scripts: From Antiquity to 1600; Dr Richard Gameson, Reader in Medieval History at Kent University and editor of St Augustine and the Conversion of England; Professor Clare Lees, Professor of Medieval Literature at King's College London and author of Tradition and Belief: Religious Writing in Late Anglo-Saxon England.

Melvyn Bragg and guests discuss the theories of a grand design in the universe. The late evolutionary biologist Stephen Jay Gould argued that if you re-ran the tape of evolutionary history, an entirely different set of creatures would emerge. Man would not exist because the multitude of random changes that resulted in us would never be repeated exactly the same way. Others disagree, arguing that there is a pattern that points to some kind of direction – even, perhaps, a design, a sense that some things are pre-ordained. Who were the original proponents of the idea of a grand design? Were they deliberately setting out to find a scientific theory that could sit alongside religious faith? On the other hand, can the concept of contingency – or the randomness of evolution - be compatible with a belief in God? With Simon Conway Morris, Professor of Evolutionary Palaeobiology at Cambridge University and author of The Crucible of Creation – the Burgess Shale and the Rise of Animals; Sandy Knapp, botanist at the Natural History Museum; John Brooke, Andreas Idreos Professor of Science and Religion at Oxford University.

Melvyn Bragg and guests discuss the history of the epic. In his essay 'Why the novel matters', DH Lawrence argued that the novel contained all aspects of life. Perhaps better placed to make that claim is the epic. From tackling questions of identity, history, warfare, mortality and the ways of the Gods to narrating tales of magic and supernatural creatures, it was the Greek and Roman poems of Homer and Virgil that underpinned and explained the position of men in the world. And it was these narratives of heroic actions and grand deeds that were to form a template from which many future epics would be constructed from Chaucer's Troilus and Cressayde to Milton’s Paradise Lost. But who are the heroes of these epics? To what extent was the classical epic a political project, a means of creating a founding myth for empire? How did the Renaissance revive the form and how successful were writers such as Milton in rendering the Christian story an epic? And what does the novel owe to the epic?With, John Carey, Emeritus Professor of English Literature at Oxford University; Karen Edwards, Lecturer in English at Exeter University; Oliver Taplin, Professor of Classical Languages and Literature at the University of Oxford.

Melvyn Bragg and guests discuss the calendar, which shapes the lives of millions of people. It is an invention that gives meaning to the passing of time and orders our daily existence. It links us to the arcane movements of the heavens and the natural rhythms of the earth. It is both deeply practical and profoundly sacred. But where does this strange and complex creation come from? Why does the week last seven days but the year twelve months? Who named these concepts and through them shaped our lives so absolutely? The answers involve Babylonian Astronomers and Hebrew Theologians, Roman Emperors and Catholic Popes. If the calendar is a house built on the shifting sands of time, it has had many architects. With Robert Poole, Reader in History at St Martin’s College Lancaster and author of Time’s Alteration, Calendar Reform in Early Modern England; Kristen Lippincott, Deputy Director of the National Maritime Museum in Greenwich; Peter Watson, Research Associate at the McDonald Institute for Archaeological Research at Cambridge University and author of A Terrible Beauty – A History of the People and Ideas that Shaped the Modern Mind.

Melvyn Bragg and guests discuss man and disease. The Book of Exodus makes clear that when God wants to strike humankind, he does so with plague and disease. For millennia epidemics were understood exactly that way - as acts of divine retribution, a force of nature that could devastate empires and annihilate great swathes of population at a stroke. From the bubonic plague to measles, from cholera to smallpox, epidemics have constantly reshaped our world, leaving destruction and huge social upheaval in their wake. Before advanced science, what defences did humankind have? How much did the ancient Greeks understand of the root causes of disease - or did they simply explain it as an imbalance of the four humours that governed the body? What were the social and political consequences of The Black Death of 14th century Europe which wiped out a third of the population? How did the scientific breakthroughs of the 19th century - and the discovery of germ theory - alter people's perception of disease? And is it possible to live in a disease free society? How have we understood these afflictions, how have we fought against them and is it a war we can ever win?With Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre at University College London; David Bradley, Professor of Tropical Hygiene at the London School of Hygiene and Tropical Medicine; Dr Chris Dye, epidemiologist with the World Health Organisation.