Melvyn Bragg and guests discuss the shape of the universe. In the Beginning, runs one account, was the Big Bang. All matter in existence today originated around 13 billion years ago in a phenomenally hot, extraordinarily condensed primordial atom that exploded with incredible force. Hydrogen and helium were shot across the firmament, gravity caused the gases to condense into clouds and in these clouds the first stars were formed, then galaxies came and more galaxies in clusters, onwards and outwards, ever expanding. It is still expanding, runs the orthodox account, and may even be speeding up. It is still creating new galaxies and it continues to colonise more and more of infinite space, despite the fact that it is supposedly infinite itself.So, if our universe is expanding, what is it expanding into? If it is already infinite how can it be getting any bigger? And is there really only one?With Sir Martin Rees, Royal Society Research Professor in Astronomy and Physics, Cambridge University; Julian Barbour, Independent Theoretical Physicist; Janna Levin, Advanced Fellow in Theoretical Physics at the University of Cambridge.

Melvyn Bragg examines one of the greatest scientific breakthroughs of the 20th century, and certainly the most controversial; the development of nuclear physics. Harnessing the enigmatic qualities of the atom’s tiny core brought us nuclear power and gave us The Bomb, a breakthrough with such far-reaching consequences that it moved the physicist Albert Einstein to say, “Had I known, I should have become a watch maker”.How can such outlandish power be released from such infinitesimal amounts of matter and what does the science of the nucleus tell us about how our universe is built? Nuclear technology provokes strong emotional and political reactions, but what are the plain facts behind its development as a science? With Jim Al-Khalili, Senior Lecturer in Physics at the University of Surrey; Christine Sutton, Particle Physicist and Lecturer in Physics at St Catherine’s College Oxford; John Gribbin, Visiting Fellow in Astronomy at the University of Sussex.

Melvyn Bragg looks at the development of the science of genetics. In the 1850s and 60s, in a monastery garden in Burno in Moravia, a Franciscan monk was cultivating peas. He began separating the wrinkly peas from the shiny peas and studying which characteristics were passed on when the next crop of peas were grown. In this slow and systematic way Gregor Mendel worked out the basic law of heredity and stumbled upon what was later to be described as the fundamental unit of life itself…the gene.But Mendel’s work was ignored when he published his findings in 1865, and it was not until the 20th century that he was rediscovered and the science of genetics was born. What effect did the discovery of the gene have on Darwin’s ideas? How do our genes work upon us, and how can we manipulate them?With Steve Jones, Professor of Genetics and Head of the Galton Laboratory at University College London, Richard Dawkins, Charles Simonyi Professor of the Public Understanding of Science at Oxford University and the genetic scientist Linda Partridge, NERC Research Professor at the Galton Laboratory, University College London.

Melvyn Bragg and guests discuss the science of Oceanography. In 1870 Jules Verne described the deep ocean in 2,000 Leagues Under the Sea. He wrote: “The sea is an immense desert where man is never alone for he feels life, quivering around him on every side.” This was actually closer to the truth than the science of the time, when ‘Azoic Theory’ held sway and it was believed that nothing could exist below 600 metres. Now we estimate that there are more species in the deep ocean than in the rest of the planet put together, somewhere between 2 million and 100 million different species of organism are living on the ocean floor.Science has dispelled the idea that huge underground tunnels join our oceans together and the notion that giant Kraken lurk in the deep, but our seas still retain much of their mystery and there have been more men on the surface of the moon than at the bottom of the ocean. How should we understand the sea? With Margaret Deacon, visiting Research Fellow at Southampton Oceanography Centre and author of Scientists and the Sea, Tony Rice, Biological Oceanographer and author of Deep Ocean, Simon Schaffer, Reader in History and Philosophy of Science at the University of Cambridge, and a fellow of Darwin College.

Melvyn Bragg discusses the origin of the Earth. Ideas used to be very clear about its origins. Bishop Ussher, in 1654 arrived at an exact figure and specified it in his work Annalis Veteris et Novi Testamenti: He deduced that work on Planet Earth began at exactly 9am, on Monday 23rd October 4004 BC. The date was then printed in the margin of The Bible and preached from the pulpit, and right up to the nineteenth century to the left of ‘In The Beginning…’ was specified ‘Before Christ 4004’.Christian believers thought the creation story was solid as a rock…until the geologists arrived. First Hutton, then Smith, and then Lyell smashing away at orthodox belief in a way that made poor Ruskin quail, but in doing so they created a science. With Simon Winchester, author of The Map That Changed the World: the Tale of William Smith and the Birth of A Science; Cherry Lewis, geologist and author of The Dating Game: One Man’s Search for the Age of the Earth; John Cosgrove, Structural Geologist from the Royal School of Mines at Imperial College, London.

Melvyn Bragg and guests discuss Black Holes. They are the dead collapsed ghosts of massive stars and they have an irresistible pull: their dark swirling, whirling, ever-hungry mass has fascinated thinkers as diverse as Edgar Allen Poe, Stephen Hawking and countless science fiction writers. When their ominous existence was first predicted by the Reverend John Mitchell in a paper to the Royal Society in 1783, nobody really knew what to make of the idea - they couldn’t be seen by any telescope. Although they were suggested by the eighteenth century Marquis de Laplace and their existence was proved on paper by the equations of Einstein’s General Theory of Relativity, it was not until 1970 that Cygnus X 1, the first black hole, was put on the astral map. What causes Black Holes? Do they play a role in the formation of galaxies and what have we learnt of their nature since we have found out where they are?With the Astronomer Royal - 2001 Sir Martin Rees, Professor of Physics and Astronomy at Cambridge University; Jocelyn Bell Burnell, Professor of Physics at The Open University; Professor Martin Ward, director of the X-Ray Astronomy Group at the University of Leicester.

Melvyn Bragg and guests discuss the significance of fossils. In the middle of the nineteenth century the discoveries of the fossil hunters used to worry poor Ruskin to death, he wrote in a letter in 1851, “my faith, which was never strong, is being beaten to gold leaf…If only those Geologists would let me alone I could do very well, but those dreadful Hammers! I hear the clink of them at the end of every cadence of the Bible verses.”The testimony of fossils over the ages has been remarkably eloquent when we have wanted to listen; and now with mass spectrometers, electron microscopes and secondary X-ray detectors, these long dead organisms can speak to us of the past in ways they never could before.With Richard Corfield, Research Associate in the Department of Earth Sciences at Oxford University; Dianne Edwards, Distinguished Research Professor in Palaeobotany at Cardiff University; Richard Fortey, Senior Research Palaeontologist at the Natural History Museum.

Melvyn Bragg examines Quantum Gravity. Early in the 20th century physicists were startled by the realisation that the smallest things in the universe do not obey Newton’s laws of gravity. Ripe apples fall from trees, billiard balls roll mostly on the table and the moon orbits the Earth in thrall to its gravitational pull, but there is no such force of gravity at work in the world of very small things. It seems there is one set of rules for the realm of every day objects, and a very different set of laws for the quantum world - where tiny particles actually form the building blocks of all those larger things.But how can this be? It doesn’t appear to make sense. Physicists decided that there must be another theory - a much larger theory - that unites, incorporates and finally makes sense of these divided realms. And this has been the Holy Grail of physics ever since. With Dr John Gribbin, Visiting Fellow in Astronomy, University of Sussex; Lee Smolin, Professor of Physics, Centre for Gravitational Physics and Geometry, Pennsylvania State University and Visiting Professor of Physics at Imperial College, London; Dr Janna Levin, Advanced Fellow, Department of Applied Mathematics and Theoretical Physics, Cambridge University.

Melvyn Bragg and guests discuss what drove the British Empire, especially in Victoria’s century. Was it science, more specifically, the science of plants, of agriculture, a scientific notion of nature and the improvement of nature? Was this seemingly rather adjacent notion - that the source of Empire can be found in Kew Gardens, Royal, Botanical, rather than in the muzzle of a gun or in the purse of a plunderer or in the consciousness of a conqueror - was science “the force that was with us?” Francis Bacon said of the Irish in 1603, “We shall reclaim them from their barbarous manners…populate plant and make civil all the provinces of that kingdom ..as we are persuaded that it is one of the chief causes for which God hath brought us to the Imperial Crown of these Kingdoms”. Centuries later, at the height of the Empire, John Stuart Mill wrote in On Liberty: “Despotism is a legitimate mode of government in dealing with barbarians, provided the end be their improvement”. But - despotism aside - was this notion of ‘improvement’ really the driving force behind the Empire? And did the British Empire have any firm basis in believing that the ‘light of pure reason’ that it brought to its colonies was any brighter than the knowledge that existed before they came? With Richard Drayton, Professor of History at the University of Virginia and author of Nature’s Government: Science, Imperial Britain and the ‘Improvement’ of the World; Maria Misra, Lecturer in Modern History and fellow of Keble College Oxford; Ziauddin Sardar, Professor of Science and Technology Policy, Middlesex University.

Melvyn Bragg looks at the deep claims made for mathematics, the discipline some believe to be the soul and true key to the understanding of all life, from the petals on the sunflower to the pulse in our wrists. The notion that mathematics is akin to theology might take some taking in at first. But from the first, in the West, they were. To Pythagoras, numbers were mystical and “prove” God. To Plato, who, it is claimed, has driven mathematics for over two thousand years, the ideals beyond the reality of our lives are to be found in mathematical perfections, immutable truth, God again in numbers. Are mathematics there in the universe, waiting to be discovered as the great ocean lying before Newton - or are they constructs applied by us to the universe and imposed rather than uncovered? It’s a long way from chalky sums on the blackboard and the first careless swing of the compass. Galilei Galileo wrote, “The Universe cannot be read until we have learnt the language and become familiar with the characters in which it was written. It is written in mathematical language, and the letters are triangles, circles and other geometrical figures, without which means it is humanly impossible to comprehend a single word”. But is he right that mathematics is the script in which the universe was written, or is it really just one of many possible systems that humankind has invented to interpret our world? Is mathematics is a process of invention or a voyage of discovery?With Ian Stewart, Professor of Mathematics and Gresham Professor of Geometry, University of Warwick; Margaret Wertheim, science writer, journalist and author of Pythagoras’ Trousers; John D Barrow, Professor of Applied Mathematics and Theoretical Physics, University of Cambridge.