Dhru Purohit Show

Inflammation of the Brain is Making Us Foggy, Depressed, and Anxious - Here’s How to Fix It By Protecting Our Mitochondria


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This episode is brought to you by LMNT, Lumebox, and Seed Oil Scout.


By conservative estimates, at least 88% of people have insulin resistance, which significantly impacts brain health and the brain’s ability to produce energy. In today’s episode, I’m sharing some of the latest research on brain health, the critical role of mitochondria in maintaining optimal brain function, and how insulin resistance and metabolic dysfunction can disrupt mitochondria, leading to poor brain health.


Today on The Dhru Purohit Show, we have a special compilation episode featuring Dhru’s conversations with guests on how inflammation affects both metabolic and brain health. Dr. Georgia Ede explains why oxidative stress and insulin resistance have surged with the rise of refined carbohydrates and seed oils. Dr. Chris Palmer shares the latest research on how mitochondria influence neurotransmitter production, hormone regulation, and gene expression—and what can lead to mitochondrial dysfunction. Hannah Warren discusses her journey to overcome mental illness by applying Dr. Palmer’s Brain Energy theory and using ketosis to rejuvenate mitochondria.


Dr. Georgia Ede. Dr. Ede is a board-certified psychiatrist specializing in college mental health and nutritional psychiatry. She has 18 years of clinical experience in hospitals, community health centers, specialty clinics, and private practices, utilizing medications and psychotherapy to help adults of all ages.


Dr. Chris Palmer is a psychiatrist and researcher at metabolism and mental health interface. He has pioneered the use of the medical ketogenic diet in the treatment of psychiatric disorders through research, patient treatment, writing, and speaking around the world on this topic. More broadly, he is interested in the roles of metabolism and metabolic interventions on brain health.

Hannah Warren joined the Baszucki Group and its Metabolic Mind initiative in November 2023 as Mental Health Communications and Advocacy Manager. Hannah volunteers with the Brain Energy Movement, started by Dr. Christopher Palmer, to spread awareness of the brain energy theory.


In this episode, Dhru and his guests dive into: 

  • Dr. Georgia Ede - Driving forces behind mental health problem (01:53)
  • The addition of two categories of food: refined carbohydrates and seed oils (09:02)
  • Insulin resistance (13:32)
  • Basics of the brain (20:47)
  • Dr. Chris Palmer explains the critical role of mitochondria in brain health and mental health (23:58)
  • What causes mitochondrial dysfunction (30:28)
  • Studies showcasing how mitochondria impact neurological conditions (32:44)
  • Hannah Warren - Implementing Dr. Palmer’s Brain Energy metabolic therapy (42:00)
  • The importance of metabolic flexibility (44:25)
  • What is the Brain Energy Theory (47:19)
  • Final thoughts (51:51)

  • Also Mentioned:

    • Dr. Ede’s book Change Your Diet, Change Your Mind 
    • Dr. Ede’s Website
    • Dr. Chris Palmer’s book Brain Energy 

    • This episode is brought to you by LMNT, Lumebox, and Seed Oil Scout. 


      Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.


      Lumebox is having their biggest sale of the year and is offering my community almost 50% off their FDA-registered portable Red Light device! Just go to thelumebox.com/dhru to get your device today!


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      Dhru Purohit ShowBy Dhru Purohit

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