Enhance your patient care skills with this season covering select AGA Clinical Practice Updates.

This episode shares key insights from the AGA Clinical Practice Update: Diagnosis and Management of Cyclic Vomiting Syndrome (published in the September 2024 issue of Gastroenterology). We dive into why gastroenterologists and hepatologists should think about a diagnosis of cyclic vomiting syndrome when seeing patients who report recurrent nausea and vomiting symptoms and discuss strategies for therapy.

This episode is hosted by Dr. Kyle Staller, CPU author and member of the AGA Clinical Practice Updates Committee. He is joined by fellow authors:

-Dr. David Levinthal, assistant professor of medicine at the University of Pittsburgh and director of the UPMC Neurogastroenterology and Motility Center

-Dr. Thangam Venkatesan, professor of internal medicine and head of the neurogastroenterology and motility section at The Ohio State University Wexner Medical Center

To access the full Clinical Practice Update, visit www.gastro.org/CPU.

Enhance your patient care skills with this season covering select AGA Clinical Practice Updates.

This special episode of Inside Scope shares key insights from the AGA Clinical Practice Update on Alpha-Gal Syndrome for the GI Clinician.

Originally released as a bonus episode March 2024, this episode shares key insights from the AGA Clinical Practice Update (CPU) on Alpha-Gal Syndrome for the GI Clinician (published in the April 2023 issue of Clinical Gastroenterology and Hepatology).

This episode is hosted by Dr. Jana Al Hashash, chair-elect of the AGA Clinical Practice Update Committee and one of the CPU authors. She is joined by her co-authors:

-Dr. Sarah McGill, gastroenterologist and associate professor of medicine at the University of North Carolina

-Dr. Thomas Platts-Mills, professor of medicine and microbiology and chief at the University of Virginia, a pioneer in discovery of alpha-gal syndrome

-Dr. Hannah Dodson, nurse Practitioner affiliated with the University of North Carolina and a patient sharing her perspective on navigating life with alpha-gal syndrome

To access the full Clinical Practice Update, visit https://www.gastro.org/CPU

Enhance your patient care skills with this season covering select AGA Clinical Practice Updates.

Originally released as a bonus episode in June 2023, this episode shares recommendations from the AGA Clinical Practice Update (CPU) on the Endoscopic Approach to Recurrent Acute and Chronic Pancreatitis (published in the October 2022 issue of Gastroenterology).

This episode is hosted by Dr. Jana Al Hashash, chair of the AGA Clinical Practice Update Committee and an author of this CPU. She is joined by:

Dr. Greg Coté, professor of medicine at Oregon Health Science University.

Dr. Daniel Strand, associate professor of interventional endoscopy at University of Virginia.

Dr. Ryan Law, doctor of osteopathic medicine at the Mayo Clinic, Rochester.

To access the full Clinical Practice Update, visit www.gastro.org/CPU.

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode two, our host Muhamad Nadeem Yousaf, MD, speaks with Nikki Duong, MD, to discuss the nomenclature, pharmacological options, and care recommendations for HRS-AKI patients.

Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI.

To read the related journal articles and claim CME for listening, visit agau.gastro.org.

This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode three, our host Muhamad Nadeem Yousaf, MD, speaks with Nikhilesh Mazumder, MD, MPH, Shilpa Junna, MD, and Pratima Sharma, MD, MBBS, MS, to discuss initial management of patients with HRS-AKI. They’ll explore topics such as the efficacy of non-selective beta-blockers, the recommended plasma expander for those with decompensated cirrhosis, the roles of renal replacement therapy (RRT), TIPS, and extracorporeal liver support system (ELSS), and the significance of liver transplant in the context of HRS-AKI.

Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI.

To read the related journal articles and claim CME for listening, visit agau.gastro.org.

This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In our final episode, our host Muhamad Nadeem Yousaf, MD, speaks with Vivian Ortiz, MD, and Neil Shah, MD, to delve into critical aspects of HRS-AKI. They cover the prognosis after initial management, the significance of reversing renal impairment for liver transplant candidates, the predictive role of MELD score in HRS-AKI, treatment's impact on liver transplant waiting lists, decision-making between liver transplant alone or simultaneous liver-kidney transplant, timing considerations for kidney transplant post-liver transplant, and factors affecting post-transplant prognosis.

Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI.

To read the related journal articles and claim CME for listening, visit agau.gastro.org.

This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode one, our host Muhamad Nadeem Yousaf, MD, speaks with Danielle Adebayo, MD, and Florence Wong, MD, MBBS, FRCPC, to analyze the pathophysiology of HRS-AKI. They cover peripheral vasodilatation hypothesis shortcomings in HRS-AKI, vasoconstrictor systems, bacterial translocation, inflammation, renal dysfunction, and contributory factors like cholemic nephropathy and adrenal insufficiency, while also suggesting the potential of metabolomic studies for future insights.

Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI.

To read the related journal articles and claim CME for listening, visit https://agau.gastro.org/cw/course-details?entryId=14556831&subscribed=true.

This series is supported by an independent educational grant from Mallinckrodt

Dr. G.S. Raju, editor of the Gastro Grand Rounds section in Gastroenterology, is joined by Drs. Marwan Ghabril and Naga Chalasani to discuss their Gastro Grand Rounds article, "A 68-Year-Old Woman With Unexplained Liver Enzyme Elevation and Active Chronic Hepatitis: Beware of Drug-Induced Autoimmune-Like Hepatitis." https://www.gastrojournal.org/article/S0016-5085(23)05078-3/fulltext

Dr. Ghabril is a professor of medicine at Indiana University School of Medicine. Dr. Chalasani is the David W. Crabb professor of gastroenterology and hepatology and an adjunct professor of anatomy, cell biology, and physiology at Indiana University School of Medicine.

[0:27] Introduction of the authors and outline of the case.

[3:30] Initial thoughts from the authors upon patient presentation.

[7:29] After considering additional patient history, what do the authors think about the patient?

[10:34] Does the family history of the patient cause the authors to refine the diagnosis?

[11:52] Further thoughts from the authors after physical examination of the patient.

[14:47] What tests are recommended?

[18:55] Additional thoughts from the authors after further testing.

[21:06] Should we be testing for hepatitis E?

[22:56] Should noninvasive testing be used?

[25:11] What is the authors' plan to determine next steps?

[27:06] How long should the wait be before a biopsy?

[29:08] The patient underwent liver biopsy. How were the results interpreted?

[34:31] How long does it take to determine that an appropriate course of action was made?

[35:37] How is the patient counselled?

[38:43] The LiverTox database.

[41:41] Final thoughts from the authors.

Thank you for listening. Find this and other articles on our website at https://www.gastrojournal.org. We welcome your feedback. Please email us at [email protected].

This discussion was recorded on Dec. 20, 2023, and reflects medical knowledge at that time. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent those of the American Gastroenterological Association. The content of this podcast is provided for general information purposes only and does not offer medical or any other type of professional advice.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials.

In this supersized episode, co-host Dr. Ayanna Lewis is joined by guest Dr. Ryan Stidham, an associate professor at the University of Michigan holding appointments in the departments of medicine and computational medicine. Dr. Stidham is a medical data scientist and has a research program that focuses on the development and testing of new technologies for disease assessment and decision making in gastroenterology and general medicine. Today’s discussion will explore how artificial intelligence may help address challenges with participant recruitment for clinical trials, while also discussing the role of AI in the field of gastroenterology more broadly.

This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials.

In this episode, co-host Dr. Ayanna Lewis is joined by guest Dr. Erica Cohen, an adult gastroenterologist, IBD specialist and director of the IBD Research Program at Capital Digestive Care in Washington, D.C. Today’s discussion focuses on the community GI’s perspective on clinical trials.

This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.