A hundred years from now, "physicians will have the capacity to keep people alive indefinitely,” says Dr. Michael Rose, director and professor in the Department of Ecology and Evolutionary Biology at the University of California, Irvine. Dr. Rose has spent over 40 years working with fruit flies to try to unravel the mechanisms at work as we age. He believes that there is a point (which can be manipulated) in our lives, when aging ends. It is followed by a "post-aging phase of biological immortality" before we die. Dr. Rose, co-founder of Lyceum Pharmaceuticals, a research startup in California, focuses on trying to "re-tune" patterns of aging to help us live longer and better lives. In this in-depth interview, he explains his “four-steps to the conquest of aging,” and the importance of living an “age appropriate lifestyle."

Phil Libin, co-founder and former CEO of Evernote, the note-taking app, recently moved into a new phase of his life. He turned 45, launched a new AI startup studio, All Turtles, and perhaps most significantly, lost a ton of weight. Phil has been a big guy since his late teens. He knew he was obese but did nothing about it until eight months ago. That’s when he decided to join the growing clan of fasting enthusiasts in Silicon Valley. It worked. He has lost 86 pounds (39 kilograms). Blood tests suggest he could be 20 years younger. And here’s the kicker: Phil says he plans to continue fasting indefinitely - not because he needs to lose much more weight but because he enjoys a sustained feeling of "mild euphoria" while not eating. He fasts periodically for up to eight days at a time. In this in-depth interview, Phil explains why his extreme regime is so invigorating; how he pushed back at his doctor, who thought it was a bad idea; and why he likens fasting to skydiving. 

PartiQlar supplements

Enhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin.
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Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Phil Libin, co-founder and former CEO of Evernote, the note-taking app, recently moved into a new phase of his life. He turned 45, launched a new AI startup studio, All Turtles, and perhaps most significantly, lost a ton of weight. Phil has been a big guy since his late teens. He knew he was obese but did nothing about it until eight months ago. That’s when he decided to join the growing clan of fasting enthusiasts in Silicon Valley. It worked. He has lost 86 pounds (39 kilograms). Blood tests suggest he could be 20 years younger. And here’s the kicker: Phil says he plans to continue fasting indefinitely - not because he needs to lose much more weight but because he enjoys a sustained feeling of "mild euphoria" while not eating. He fasts periodically for up to eight days at a time. In this in-depth interview, Phil explains why his extreme regime is so invigorating; how he pushed back at his doctor, who thought it was a bad idea; and why he likens fasting to skydiving.

As human life expectancy continues to increase, age-related diseases are the main impediment to enjoying the fruits of longevity. High on the list is Alzheimer’s disease, the incurable neurodegenerative condition that robs sufferers of their memory and eventually leads to death. But valuable progress is being made in the understanding and prevention of the disease. A new study at the Keck School of Medicine of USC in Los Angeles has revealed that biological changes in the brain occur long before symptoms of Alzheimer’s become apparent. The research, led by neuropsychologist Dr. Duke Han, suggests that cognitive tests are able to detect early stage of the disease in people without symptoms. In this in-depth interview, Dr Han argues that routine brain testing should be incorporated into annual physical check ups for people of all ages.

PartiQlar supplements

Enhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin.
Get a 15% discount with the code MASTERAGING15 at PartiQlar

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

As human life expectancy continues to increase, age-related diseases are the main impediment to enjoying the fruits of longevity. High on the list is Alzheimer’s disease, the incurable neurodegenerative condition that robs sufferers of their memory and eventually leads to death. But valuable progress is being made in the understanding and prevention of the disease. A new study at the Keck School of Medicine of USC in Los Angeles has revealed that biological changes in the brain occur long before symptoms of Alzheimer’s become apparent. The research, led by neuropsychologist Dr. Duke Han, suggests that cognitive tests are able to detect early stage of the disease in people without symptoms. In this in-depth interview, Dr Han argues that routine brain testing should be incorporated into annual physical check ups for people of all ages.

Why do women live longer than men? Does the ability to bear children play a role and to what extent do evolutionary forces discriminate between men and women? 

Dr. Felice Gersh is a board-certified (1984) gynecologist and the founder of a private medical practice, the Integrative Medical Group of Irvine, California. Fellowship trained in a relatively new medical field, known as functional/integrative medicine, Dr. Gersh believes longevity is connected to estrogen. She argues that it is the “most maligned and insulted” of all hormones and acts a natural anti-inflamatory agent to promote good health in both women and men. 

Dr. Gersh advocates for a better understanding of the role stomach bacteria play in living a long, healthy life. She believes doctors should “expand their tool boxes” to include acupuncture, herbal medicine and meditation. In this interview she  explains why she “had to unlearn” much of what she learned at medical school and calls for a fundamental shake-up in the delivery of health care.

PartiQlar supplements

Enhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin.
Get a 15% discount with the code MASTERAGING15 at PartiQlar

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Why do women live longer than men? Does the ability to bear children play a role and to what extent do evolutionary forces discriminate between men and women? Dr. Felice Gersh is a board-certified (1984) gynecologist and the founder of a private medical practice, the Integrative Medical Group of Irvine, California. Fellowship trained in a relatively new medical field, known as functional/integrative medicine, Dr. Gersh believes longevity is connected to estrogen. She argues that it is the “most maligned and insulted” of all hormones and acts a natural anti-inflamatory agent to promote good health in both women and men. Dr. Gersh is a leading voice on women’s health issues. She advocates for a better understanding of the role stomach bacteria play in living a long, healthy life. A prolific speaker, she believes doctors should “expand their tool boxes” to include acupuncture, herbal medicine and meditation. In this in-depth interview Dr. Gersh explains why she “had to unlearn” about half of everything she learned at medical school calls for a fundamental “shake-up” in the delivery of health care.

The enhancement of the human body is the main goal of Geoffrey Woo, a biohacker and entrepreneur based in San Francisco. A Stanford-trained computer scientist, Geoffrey is the CEO and co-founder of HVMN (formerly Nootrobox), a nootropics company that melds biology and technology to optimize the human system. The evolving science behind nootropics, which are legal compounds designed to improve cognitive function, has become big business in Silicon Valley. Geoffrey sees the human body as a quantifiable and manipulable system, and the next platform for innovation and growth. Along with his employees, he is also an enthusiastic proponent of fasting, Together, they have built a vibrant community of like-minded followers, known as WeFast. They regularly deprive themselves of food, in the pursuit of good health and longevity. In this in-depth interview, Geoffrey shares his enthusiasm for biohacking and explains why he believes everyone will be fasting within the next two years.

PartiQlar supplements

Enhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin.
Get a 15% discount with the code MASTERAGING15 at PartiQlar

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The enhancement of the human body is the main goal of Geoffrey Woo, a biohacker and entrepreneur based in San Francisco. A Stanford-trained computer scientist, Geoffrey is the CEO and co-founder of HVMN (formerly Nootrobox), a nootropics company that melds biology and technology to optimize the human system. The evolving science behind nootropics, which are legal compounds designed to improve cognitive function, has become big business in Silicon Valley. Geoffrey sees the human body as a quantifiable and manipulable system, and the next platform for innovation and growth. Along with his employees, he is also an enthusiastic proponent of fasting, Together, they have built a vibrant community of like-minded followers, known as WeFast. They regularly deprive themselves of food, in the pursuit of good health and longevity. In this in-depth interview, Geoffrey shares his enthusiasm for biohacking and explains why he believes everyone will be fasting within the next two years.

James Maskell is a writer, public speaker, entrepreneur and advocate for a new paradigm in healthcare. The author of The Evolution of Medicine, James is the founder of the Functional Forum, an integrative medicine conference that curates discussions with leading medical practitioners around the world. Next week, James will co-host the launch of an ambitious project to make Guernsey the first community in the world to achieve a life expectancy of 100. Named 'Journey to 100,' the goal is to radically improve the health and longevity of people living on the island through a greater emphasis on preventative medicine, purpose in life and a proactive approach to wellbeing.

PartiQlar supplements

Enhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin.
Get a 15% discount with the code MASTERAGING15 at PartiQlar

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.