In this episode of the LiverHealthPOD John, Will and Paul discuss "Lean MAFLD". These patients may not fit the typical metabolic stereotype, but they can still progress to fibrosis and cirrhosis. which challenges the outdated assumption that fatty liver disease is simply a consequence of obesity.

People with a “normal” BMI can still develop significant hepatic steatosis and inflammation, often driven by a combination of genetic susceptibility, visceral adiposity, insulin resistance, and environmental factors.

Find out more in this episode.

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In this episode of the LiverHealthPOD, John, will and Paul

discuss new breakthrough treatments in PBC

For decades, treatment for primary biliary cholangitis (PBC) centred on ursodeoxycholic acid (UDCA or "Urso"). But the therapeutic landscape is rapidly evolving.

In this episode of LiverHealthPOD, we explore the emerging wave of treatments transforming care for PBC.

What do these therapies mean for patients who don’t respond adequately to standard treatment? How do clinicians decide when to escalate therapy? And what might the future hold for disease modification in PBC?

Join us as we unpack the latest science and clinical advances shaping the next chapter in PBC care.

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in this episode of the LiverealthPOD, Will, John and Paul discuss CBD oil and the lvier.

CBD oil has exploded in popularity—marketed for everything from anxiety and insomnia to chronic pain and inflammation. But what does it actually do to the liver?

In this episode we unpack the science behind cannabidiol (CBD). We explore how CBD is metabolised by the liver, what the evidence says about elevated liver enzymes, and whether there are real risks of liver injury.

we tackle what clinicians and patients should know before using CBD products.

Join us as we separate evidence from hype.

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One of the most common questions we get asked in the LiverHealthPod is what about Creatine? In this episode Paul, John and Will - three liver doctors with over 60 years of collective experience in managing liver disease discuss their opinion of Creatine. If you want to hear the evidence tune into this episode of the LiverHealthPOD

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In the episode,

Will, Paul and John examine new and emerging data around the impact of diet Sodas and non-nutritive sweeteners on liver health.

Listen in to hear more and don't forget to like and subscribe and send us a message at [email protected]

In the episode,

John, Will and Paul delve deep into a recent study (J Hepatol 2025 Dec;83(6):1256-1265.doi: 10.1016/j.jhep.2025.06.005) on the health effects of calorie restriction and time restriction style of eating on liver fat and weight loss.

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In this episode Paul , will and John talk about an amazing scientific experiment called the Minnesota Starvation experiment which even 80 yrs on is still teachings things about restricting calories and our heath.

Listen in.

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In this episode Will, Paul and John talk about Ferritin. It is usually interpreted as a measure of iron stores but ferritin is much, much more than that!! It maybe telling us something really important about our health.

Listen in to find out more.

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In this episode, Paul, Will and John discuss the ins and outs of Paracetamol (some may know it as acetaminophen). What's safe and how to use it effectively. ...Also its effect on the liver!

Listen in for more information and don't forget to like and subscribe or leave a rating and review so others can find us.

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In this episode Paul John and will discuss microplastics and their impact on health and disease . Are they good, bad or indifferent?

Find out on the LiverHealthPOD.

don' t forget to send your questions through to [email protected].

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