Wil Wheaton is a well seasoned actor, recognized for his work on The Big Bang Theory, Stand By Me, Star Trek: The Next Generation, and countless other classics. He joins us this week to talk about his lifelong battle with depression and anxiety. Mayim dives into the neuroscience behind depression and explores the importance of social support. Wil shares about growing up in the industry, his tumultuous relationship with his parents, the unexpected way he met his wife Anne, and the breakdown that leads to him getting help.

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Salman “Sal” Khan, acclaimed educator and philanthropist describes his journey through the educational system and his plans to change it for the better. Originally an analyst at a hedge fund, Sal decided to leave his cushioned career in order to focus on his true passion, education. This is when https://www.khanacademy.org/ was born. Mayim and Sal discuss his vision of a world where everyone has the opportunity to receive individualized, compassionate education without the fear, stress, and anxiety of standardized tests and ranking systems. Mayim shares about her own experiences in the education system as a student and as a teacher to her children. Sal and Mayim discuss the “natural curiosity” of all human beings and comment on how the traditional education system has failed many students in many ways. 

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Mayim and Brian discuss their life experiences and dissect Brian’s transformation from "nerd" to famous comedian and the impact of being a big man. Brian recounts his time working with Mayim on the Big Bang Theory and his excitement playing Dungeons and Dragons with Mayim and other members of the team! Mayim examines recent scientific research on the therapeutic potential of this socially engaging tabletop game! The conversation leads into a discussion of coping mechanisms and subsequent discussion of Brian’s use of marijuana. Both Brian and Mayim examine the risks and benefits of marijuana use.

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Elizabeth Bachner, acclaimed midwife, acupuncturist and healer, explains how her life was seemingly perfect on paper but simply didn’t feel right. By unraveling this thread, she was guided on a path of personal and spiritual transformation that many will relate to. Elizabeth brings her extensive exploration of Easter healing and Mayim and Elizabeth delve into the neuropsychological underpinnings of naturalistic medicine. Elizabeth even leads us in group meditation (Prepare to smell some lemons)! The show examines the hardships of human experience, from cancer, birth, death, and much more.

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Oh boy, let’s see how this goes. Introducing the first of many to come, the Bevisode… where Mayim and her mother sit down to analyze previous episodes and how the topics within them relate to their shared and individual experience in life. This week Bev dissects a few core topics from some of our earliest releases. Namely, anxiety as it relates to Grace Helbig’s episode, honesty about depression shared by Leslie Jordan, the idea of holding and the mind body connection explored by Iliza Shlesinger, plus Bev's deep connection to the testimony shared by Cheyenne Jackson during his appearance.

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Mayim accompanies AJ along his journey from addiction to rehabilitation. Mayim and AJ discuss alcohol and substance use as an ongoing battle between sobriety and relapse. AJ goes into depth on the genesis of the Backstreet Boys and how his bandmates/friends helped him to see he needed help. Mayim and AJ talk about the pressures of growing up in the public eye and the difficulty of switching between "stage" personas and their own personas. The conversation segues into self-care, and AJ talks about his mountain biking, golfing, and nail painting escapades. Mayim and AJ get down to the crux of addiction: It is not about the substance, it is about why sober living is so painful.

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Mayim opens up about her days on Blossom, how she started in the industry, and the huge pressures and expectations she faced. Jaleel discusses the path which led him to fame as a teenager and talks about what it was like to have so much power at a young age. Both experienced a sense of being owned by the industry and the public and share how they were trained to be deferential to adults. While they both experienced unique opportunities, including stories of 90's NBA all star games with Michael Jordan, and stories with Karl Malone and Penny Hardaway, the conversation turns to one about Jaleel’s identity as a young black man in a predominantly white industry and the impact this had on his mental health and his outlook on his career. 

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Mayim explains the benefits and historical role of meditation with her former colleague and UCLA PHD graduate buddy Sam Harris. Sam talks about his journey discovering mindfulness through an altered state as a teenager which led him to a life dedicated to encouraging others to get in touch with their base desires through a meditative practice. How do you unlink your thoughts and uncover patterns of emotion, behavior, and beliefs that no longer serve you? How do you transcend the constructed notion of who you are to access your soul? Mayim and Jonathan get put into a meditative trance by the silky timber of Sam's voice as he tackles misperceptions about meditation and explains how to access different realms of consciousness and connect to your true self.

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Mayim brings out the introspective and reflective side of Sofia - one of the podcast world's biggest stars as they breakdown how she became the fierce, independent, and outspoken woman she is today. This spicy episode brings out Mayim's inner millennial as she and Sofia cover anxiety, boundaries, and sexual health. Sofia, an outspoken and at times unabashed spokeswoman for female sexual empowerment, talks about getting her mug shot on a t-shirt, meeting her father for the first time at 15, and how leaving her job in investment banking propelled her to internet stardom.

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Mayim explains the neurobiology of trauma and reveals her own experience working to overcome a traumatic event. Rick details the ground-breaking research his lab is doing using MDMA to treat PTSD. Rick and Mayim discuss everything from the ancient cultural origins of psychedelics and explore the "unified mystical experience of oneness" that is often brought on through the use of this medicine. Rick explains how MDMA can help free people who are stuck in a fight-or-flight response by calming their overactive amygdala while reconnecting them to disconnected memories. Jonathan volunteers Mayim for Rick's next study to get help with her on-going nightmares and Rick shares in real time the results of his most recent research which promises to change the laws and future of how we treat  PTSD.

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