In this Part 1 episode, Matt and Brian Kennedy cover various aspects of aging research, including the connection between the immune system and aging, the role of inflammation, the potential of supplements and wearables in healthspan, and insights on longevity interventions. They also discuss the challenges in the field regarding clinical practices, the influence of AI on aging research, and personal experiences with health optimization.

This is Part 1 of a two-part series—stay tuned for even more in the next episode.

00:00 Intro

02:02 What is the connection between the immune system and aging?

05:10 What’s your take on rapamycin for Parkinson’s Disease?

06:08 What about the longevity benefits of high-dose vitamin D?

08:30 Are wearable devices effective for longevity-focused individuals?

11:00 What model organisms are promising for aging research?

13:19 What do you think about maldovan dragon head extract?

14:50 How can we measure intervention success in aging?

16:23 What are your thoughts on Greg Fa’s thymus trials?

21:52 Can the difference in life expectancy between men and women be explained by body size?

24:25 Is resveratrol in food the same as in supplements?

27:45 What are your thoughts on omega-3 supplementation?

30:11 How critical is genomic instability in aging?

33:15 What is the best book on health and longevity?

35:20 What exciting research should people pay attention to?

38:54 What criticisms do you have of the aging research field?

41:31 Any recommended supplements for individuals 50+?

43:27 How can someone manage stress levels?

52:15 How can underweight individuals gain weight healthily?

55:08 Did you take the biological age test at the same time of day?

01:00:13 What’s the best way to increase grip strength?

01:02:07 Are you dropping the use of the true diagnostics test in your program?

01:09:04 Are there clinically verified microbiome tests?

01:12:40 Is aging an autoimmune disease?

01:14:13 Are there lifespan-extending interventions without anti-inflammatory properties?

01:15:40 How likely is it to extend lifespan with lifestyle changes?

01:17:34 Should individuals consider GLP-1 agonists for weight control?

01:20:18 What is AI’s potential impact on aging research?

01:25:38 What’s your vision for the future of this channel?

Producers: Tara Mei, Nicholas Arapis

Video Editor: Jacob Keliikoa

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