Send us a text

Nick talks to academic dermatologist Dr. Richard Weller about: skin health; benefits & risks of sunlight & UV radiation exposure; nitric oxide, blood pressure & cardiovascular health; vitamin D; sunscreen & tanning; the evolution of skin color & skin physiology; and more.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to biologist Dr. Christoph Thaiss, a professor at the University of Pennsylvania. His lab studies how the body detects & responds to environmental stimuli, with a focus on interactions between the gut microbiome, immune & nervous systems. They discuss: sensory systems of the body & basic principles of how they work; gut microbiome & the consequences of depleting it with antibiotics; endocannabinoids & exercise; how microbiome composition influences the brain & motivation to engage in exercise; prebiotics & probiotics; circadian rhythms & eating patterns.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to biochemist & biophysicist Dr Ryan Gumpper, a postdoc in Dr. Bryan Roth's lab at the University of North Carolina. They discuss the biochemistry, molecular biology & biophysics of serotonin receptors, including the molecular details for what happens when serotonin and tryptamines psychedelics (e.g. LSD) bind to 5HT2A receptors in the brain. They also discuss how understand these details relates to the quest to discover novel psychedelic-derived compounds with therapeutic benefits, as well as the inspiration Ryan received from reading Alexander Shulgin's famous book, PIHKAL.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to anesthesiologist & neuroscientist Dr. Alex Proekt, who runs a lab at the University of Pennsylvania, about altered states of consciousness. They discuss: NREM & REM sleep, anesthesia & anesthetic drugs like propofol; coma & vegetative states; sleeping pills like Ambien; the relationship between consciousness & the underlying brain dynamics; how ketamine differs from other anesthetics & what it does to brain activity; AI & ChatGPT.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to Jay Bhattacharya, MD, PhD, who is a professor of medicine & economics at Stanford University. They discuss various aspects of the COVID pandemic, such as: how infectious, transmissible, and deadly SARS-CoV-2 is; mRNA vaccines, how well they stop transmission vs. severe COVID, and whether they can induce negative side effects such as myocarditis; how well masks really work; Jay's inclusion in the "TwitterFiles" and the suppression of speech on social media; what he thinks of Elon Musk after meeting him; his thoughts on the future of public health governance in the US.

Related episodes:

• M&M #61: Public Health, Pandemics, Epidemiology, SARS-CoV-2 & COVID Public Policy | Martin Kulldorff

*This content is never meant to serve as medical advice

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to Dr. Sergiu Pasca, a developmental neuroscientist and professor at Stanford University. They discuss topics related to human brain development, the origins of neuropsychiatric disease like autism & schizophrenia, new technologies for studying brain development, stem cells, and recent experiments from Dr. Pasca'a lab utilizing brain "organoids," "assembloids," and human-animal transplantations.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to computational neuroscientist Dr. Zach Mainen, a neuroscientist and director of the Champalimaud Neuroscience Programme at the Centre of the Unknown in Lisbon, Portugal. His lab studies the neuroscience of decision making, neuromodulation & behavior using both experimental and computational approaches. 

They discuss: what kinds of things animal brains are actually computing, and to what extent we can think about brains like computers; the difference between neurotransmitters and neuromodulators in the brain, including some discussion of what specific neuromodulators like dopamine and serotonin do in the brain; and we also discussed some of the research his lab is starting to do on serotonergic psychedelics, including how he thinks about whether the subjective effects of psychedelics are likely to be important for the therapeutic and neuroplastic effects.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to mathematical biologist Dr. Alex Washburne about the origins of the SARS-CoV-2 virus.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to experimental psychologist Dr. Harriet de Wit, a professor at the University of Chicago whose lab studies the behavioral effects of psychoactive drugs on humans. They discuss: the effects of MDMA on emotional perception and touch sensation; the effects of microdosing LSD; THC's impact on memory.

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts

Send us a text

Nick talks to biological anthropologist & neuroscientist Dr. Terrence Deacon, who is a professor of biological anthropologist at UC-Berkeley and a leading thinker on the evolution of language, consciousness and human cognition. They discuss: how end-directed systems, such as life, can emerge from non-life; how complexity evolves once life originates; the origins of sentience and a sense of self; the evolution of the nervous system and consciousness; information, value, and "aboutness" in the universe; and more.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

• KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off
• Readwise: Organize and share what you read. 60 days FREE through link
• Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
• MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off

For all the ways you can support my efforts