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Dr. Mario Capecchi is a professor of genetics at the University of Utah & Nobel laureate. He discussed: his latest work in neurobiology, looking at the role of microglia in anxiety & Obsessive Compulsive Disorder (OCD); his Nobel Prize-winning work in molecular genetics; molecular biology & genetics; his childhood experiences as an orphan in Italy during World War II; immigrating to the US; his education & scientific career; his exercise & diet; advice for aspiring scientists; and more.

*Not medical advice.

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Dr. Adriene Beltz is an associated professor of psychology at the University of Michigan who studies the effects of sex hormones & hormonal contraception on human cognition and the brain. They discuss: sex hormones (androgens & estrogens); hormonal regulation of menstruation, puberty, and pregnancy; common forms of hormonal birth control & how they work; effects of sex hormones & hormonal birth control on cognition & the brain; and more.

*Not medical advice.

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to Dr. Matthew Hill, a neuroscientist at the University of Calgary whose lab studies how the endocannabinoid system and cannabis (marijuana) influence the brain & behavior. They discuss: endocannabinoid biology; endocannabinoid regulation of stress & anxiety; endocannabinoids & exercise; how marijuana & THC influence brain development; and more.

See previous episode with Dr. Matthew Hill: https://mindandmatter.substack.com/p/matthew-hill-endocannabinoid-system-8ff#details

More content about cannabinoids & marijuana.

*Not medical advice

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to molecular physiologist Dr. Vijay Yadav, an assistant professor at Columbia University whose lab studies the molecular & cell biology of aging, nutrition, and longevity. They discuss: the cell biology of aging; how nutrients affect aging & disease; the atypical amino acid taurine & its effects on aging; taurine clinical trials & supplementation; diet, nutrition & anti-aging effects; and more.

*Not medical advice.

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to Gül Dölen, MD, PhD, a neuroscientist at Johns Hopkins University whose lab studies social behavior, synaptic plasticity, psychedelics & evolution. They discuss: What drugs like LSD, psilocybin, ketamine, MDMA, and ibogaine have in common in terms of their molecular effects in the brain; why Dr. Gül Dölen believes all of these drugs can be described as "psychedelics"; the relationship between psychedelics and neuroplasticity vs. metaplasticity; how addictive drugs are similar to and different from psychedelics; social reward learning in rodents & critical periods of plasticity; the subjective effects of psychedelics; novel psychedelic drug development; human social behavior, mental health, and psychiatry; and more.

Check out my previous discussion with Gül Dölen.

*Not medical advice

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to Dr. Alan Davis, a clinical psychologist and Director of the Center for Psychedelic Drug Research & Education at Ohio State University. They discuss: the effectiveness of mainstream forms of psychotherapy and antidepressant medications (SSRIs) for depression; psychedelic medicine & psilocybin-assisted psychotherapy; the relevance of the subjective effects of psychedelics for their therapeutic effects; FDA approval for MDMA- and psilocybin-assisted psychotherapy in the coming years; and more.

*Not medical advice.

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to Bryan Roth, MD, PhD, a Professor of Pharmacology at the University of North Carolina. Dr. Roth has been studying the molecular mechanisms of psychedelics since the 1980s. They discuss: serotonin 2A receptors in the mammalian brain; psychedelics & neuroplasticity; classic psychedelics (e.g. LSD, psilocybin, DMT) compared to drugs like ketamine & MDMA; TrkB receptors & BDNF; engineering novel drugs & psychiatric treatment methods; latest findings in psychedelic science.

More psychedelic science content.

*Not medical advice.

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
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Nick talks to ethnopharmacologist Dr. Dennis McKenna, who is the brother of psychonaut Terence McKenna and author of the book, "The Brotherhood of the Screaming Abyss." They discuss: the lives and psychedelic adventures of Dennis & Terence McKenna; experiences with psilocybin mushrooms & DMT; Carl Jung & psychology; the medical relevance of subjective psychedelic experiences; drugs, culture & society; and more.

*Not medical advice

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Nick talks to Daniel Karlin, MD, a board-certified physician in psychiatry, addiction medicine & clinical informatics who is the Chief Medical Officer at MindMed. They discuss: psychiatry; incentives in scientific & medical research; healthcare & mental health; psychedelics; LSD for anxiety; MDMA for autism; ibogaine derivatives for addiction; patient access & care; and more.

*This content is never meant to serve as medical advice.

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• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
• SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.

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Nick talks to chemist & food scientist Dr. Selina Wang about: food quality & purity; cooking oils (avocado, olive, vegetable, etc.); fruits & vegetables; oxidation & purity of cooking oils; how to identify high quality, pure foods to purchase; and more.

*Not medical advice.

Support the show

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• Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.
• KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)
• Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
• SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.

For all the ways you can support my efforts