In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Dr. Nichola Conlon delve into the complexities of aging, focusing on the important role of NAD (Nicotinamide Adenine Dinucleotide) in cellular health and longevity. They discuss how NAD levels decline with age, the implications of this decline, and innovative strategies to boost NAD levels effectively. The conversation also touches on the limitations of IV NAD therapy, the importance of addressing inflammation, and the scientific validation behind the Nuchido Time product. Dr. Conlon shares insights into future research directions and the impact of customer feedback on product development, emphasizing the need for a comprehensive approach to enhancing cellular health.

For Audience

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Takeaways

• NAD is crucial for driving cellular repair processes.
• The decline of NAD is linked to aging and inflammation.
• Addressing root causes of NAD decline is essential.
• IV NAD therapy may not effectively increase intracellular NAD levels.
• NAD recycling is a complex process influenced by various enzymes.
• Chronic inflammation can significantly deplete NAD supplies.
• Nuchido Time aims to optimize NAD levels through a comprehensive approach.
• Customer feedback drives ongoing research and product development.
• NAD levels fluctuate throughout the day, impacting circadian rhythms.
• Future studies will explore NAD's effects on sleep and skin quality.

Chapters

00:00 Introduction and Background

04:00 The Importance of NAD in Aging

07:45 Understanding NAD Depletion and Its Causes

12:47 The Role of CD38 in NAD Dynamics

16:42 Innovative Approaches to NAD Supplementation

21:26 Comparing NAD IVs and Oral Supplements

25:12 Enhancing NAD with Ozone Therapy

28:04 Product Development and Optimization

33:47 Future Research Directions and Applications

To learn more about Dr. Nichola Conlon: Website: www.nuchido.com Email: [email protected] Social media: @nuchido @drnicholaconlon

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Gladden Longevity Podcast Disclosures

• Production & Independence

The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

• Medical Disclaimer

The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

Use of information from this podcast and any linked materials is at the listener's own risk.

• Podcast Guest Disclosures

Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

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To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

• Additional Note on Content Integrity

All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.