Dhru Purohit Show

Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How to Reduce Your Risk of Cognitive Decline at Any Age, and How to Build a Super-Brain with Louisa Nicola


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We know that the seeds of Alzheimer’s disease are planted at least twenty years before a diagnosis. It’s never too early to think about the lifestyle changes that can influence brain health and reduce the risk of developing neurodegenerative diseases. With all the health and wellness advice out there, it can be challenging to know what to prioritize and what truly matters when it comes to protecting our brain health. Today’s guest breaks it down for us and gives us actionable steps we can implement immediately, regardless of age.


Today on The Dhru Purohit Show, Dhru sits down with neurophysiologist Louisa Nicola. Louisa shares the top three lifestyle factors that can influence our risk for Alzheimer’s disease. She helps us sort through the most current research and uncovers the biggest myths. She also shares the top two supplements that are critical for protecting brain health and the optimal prescription for exercise and resistance training. Looking to protect your brain health? Louisa shows us how.


Louisa Nicola, an Australian-born neurophysiologist and sports scientist, has made significant strides in the field of brain performance and human potential. In 2016, she founded Neuro Athletics, a consulting firm dedicated to optimizing brain health and performance for athletes, executives, and high performers. Louisa's innovative methods improve reaction times, decision-making, and mental acuity. Her vision is to expand Neuro Athletics' reach, empowering more individuals to achieve their full potential through enhanced brain function and mental resilience.


In this episode, Dhru and Louisa dive into (audio version / Apple Subscriber version):

  • The alarming increase in Alzheimer's disease despite genetics (00:00:36 / 00:00:36)
  • Why sleep is a critical factor in preventing disease (2:55 / 2:55)
  • The impact of a sedentary lifestyle on increasing your risk for Alzheimer’s disease and tips for beginners (14:00 / 10:30)
  • Physiology as we age (28:00 / 24:30)
  • Fundamental pillars of nutrition and the power of Omega3 fatty acids (36:00 / 31:43)
  • Creatine for neuroprotection, energy, and reversing osteoporosis (49:00 / 44:14)
  • The biggest myth about Alzheimer’s disease (56:00 / 51:10)
  • What motivated Louisa to study Alzheimer’s disease (1:03:00 / 58:02) 
  • Actionable steps you can implement to reduce your risk (1:07:00 / 1:02:10)
  • Implementing sauna into your routine to induce good stress (1:10:00 / 1:05:30)
  • Brain optimization beyond the fundamentals (1:13:00 / 1:08:40)
  • Social connections that power health (1:21:00 / 1:16:30)
  • Bigger Muscles-better brain health (1:29:00 / 1:24:30) 

  • Also mentioned in this episode:

    • Omega Quant Test
    • Neuroathletics Instagram
    • Sleep Regularity as a Predictor of All Cause Mortality Study 

    • For more on Louisa, follow her on Instagram, Twitter, and YouTube, or visit her website.


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