Dhru Purohit Show

Overlooked and Shockingly Simple Tools to Assess and Mitigate the Risk of Alzheimer’s Disease with Dr. David Perlmutter


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This episode is brought to you by Momentous and AquaTru.


According to today’s guest, the roots of Alzheimer’s are planted decades before symptoms appear. That means it’s never too early to take action. Today’s guest, Dr. David Perlmutter, shares powerful lifestyle strategies to protect your brain and lower your risk of neurodegenerative disease.


Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. David Perlmutter to discuss research on the top four factors that can determine the risk of developing Alzheimer’s and his lifestyle tips for prevention. Dr. Perlmutter shares the tools we can use to analyze our brain’s energy use and discusses the importance of engaging in physically and mentally stimulating activities. 


Dr. David Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain and Drop Acid. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease. He has published extensively in peer-reviewed scientific journals, including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition.


In this episode, Dhru and Dr. Perlmutter dive into:

  • How belly measurements can reveal metabolic health (01:21)

  • Four key factors that determine Alzheimer’s risk (6:00)

  • The impact of refined carbs vs. colorful foods on brain health (8:10)

  • How blood pressure and nitric oxide affect cognitive function (11:08)

  • The surprising connection between the oral microbiome and brain health (19:54)

  • Tools to assess how efficiently the brain uses energy (22:54)

  • How a sedentary lifestyle increases the risk of cognitive decline (25:12)

  • Final thoughts and takeaways (27:34)

    Also mentioned:

    • Full episode with Dr. David Perlmutter


      This episode is brought to you by Momentous and AquaTru Shower.


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      Right now, AquaTru is offering my community $50 off their new shower filter. Ready to upgrade your shower? Visit dhrupurohit.com/shower to experience the AquaTru Shower difference. 


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