Dhru Purohit Show

PhD Shares One of the Most Critical Antioxidants in the World for Longevity, Gut Health, Sleep, and Disease Prevention with Dr. Deanna Minich


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This episode is brought to you by Bon Charge, Lifeforce, and Lumebox


What if we told you there’s a holy grail of molecules that can prevent early aging, promote longevity, and help prevent dementia and Alzheimer’s? This super powerful hormone, neurotransmitter, and antioxidant is melatonin. Today’s episode is a masterclass on melatonin and its crucial role in our bodies.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Deanna Minich to discuss the crucial role of melatonin in our body as an antioxidant, anti-inflammatory, and circadian regulator. Dr. Minich reveals early warning signs of low melatonin levels and lifestyle habits that can disrupt its production. She also covers the latest research on melatonin and critical considerations for supplementation. If you are looking for a deep dive into melatonin, this episode is for you. 

Dr. Deanna Minich is a nutrition researcher, educator, and functional medicine-trained clinician with a unique approach to nutrition that combines physiology and psychology. She has served on the Institute of Functional Medicine’s Nutrition Advisory Board and curriculum committee and is a faculty member teaching nutrition for the Advanced Practice Module for Environmental Health. She currently serves on the Board of Directors for the American Nutrition Association and is President of the American College of Nutrition. 


In this episode, Dhru and Dr. Minich dive into (audio version / Apple Subscriber version):

  • The Crucial Role Melatonin Plays In the Body (00:00:33 / 00:00:33)
  • Early Warning Signs That Your Melatonin Is Low (2:22 / 2:22)
  • Melatonin Production and The Circadian System (9:35 / 6:15)
  • Brain Health and Preventing Alzheimer’s (13:06 / 9:46)
  • Lifestyle Habits That Disrupt Melatonin and Corrective Measures (17:34 / 14:14)
  • Melatonin Supplements and Synthetic Production and Testing (29:16 / 24:15)
  • The Research: What We Know (38:00 / 33:00)
  • How Melatonin Is Made (43:00 / 38:00)
  • Who Should and Should Not Take Melatonin (50:41 / 45:40)
  • The Rebound Effect (1:02:00 / 57:00) 
  • Melatonin As a Routine Supplement (1:06:30 / 1:01:30)
  • Personalization For Your Phenotype (1:10:50 / 1:05:50)

  • *Dr. Minich’s note about the animal study mentioned: Seasonal breeders, like mice, use changing light and melatonin to regulate reproduction. In animals living in cold climates like Canada, breeding is timed with daylight changes to avoid winter births when conditions are harsh. Humans, however, are not seasonal breeders and can reproduce year-round. If melatonin caused infertility in humans, it would be widespread, which it is not. Melatonin helps counteract infertility caused by environmental toxins due to its anti-inflammatory and antioxidant effects.


    Also mentioned in this episode:

    • Herbatonin


    To learn more about Dr. Minich, follow her on Instagram, Twitter, or her website.


    This episode is brought to you by Bon Charge, Lifeforce, and Lumebox. 

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