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In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, explains why progesterone delivery systems matter—and how different routes change what progesterone actually does in the body.
Part 4 of the progesterone series covers oral, topical, vaginal, rectal, injectable, and sublingual progesterone, breaking down which methods affect the brain, uterus, and breast tissue—and why choosing the right route is critical.
If progesterone hasn’t worked for you in the past, the issue may not be the dose, but how it was delivered.
This episode focuses on education, patient agency, and thoughtful hormone care—no shortcuts, no selling.
Subscribe for more in-depth conversations on hormones and women’s health, and share with someone who may benefit.
Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start.
👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it.
📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604
📲 Follow Dr. McCarthy:
Instagram: @drbrendanmccarthy
TikTok: @drbrendanmccarthy
Website: www.protealife.com
💬 Got a question or topic for a future episode? Let us know in the comments!
By Dr. Brendan McCarthy4.7
2020 ratings
In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, explains why progesterone delivery systems matter—and how different routes change what progesterone actually does in the body.
Part 4 of the progesterone series covers oral, topical, vaginal, rectal, injectable, and sublingual progesterone, breaking down which methods affect the brain, uterus, and breast tissue—and why choosing the right route is critical.
If progesterone hasn’t worked for you in the past, the issue may not be the dose, but how it was delivered.
This episode focuses on education, patient agency, and thoughtful hormone care—no shortcuts, no selling.
Subscribe for more in-depth conversations on hormones and women’s health, and share with someone who may benefit.
Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start.
👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it.
📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604
📲 Follow Dr. McCarthy:
Instagram: @drbrendanmccarthy
TikTok: @drbrendanmccarthy
Website: www.protealife.com
💬 Got a question or topic for a future episode? Let us know in the comments!

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