By Jay Feldman Wellness
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The podcast currently has 120 episodes available.
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-119-vitamin-a-toxicity-examining-the-evidence-for-vitamin-a-deficiency
Timestamps:
0:00 – intro
1:09 – why we’re discussing vitamin A toxicity and Grant Genereux’s perspective
4:53 – closedmindedness within the “low vitamin A” sphere and how it compares to Ray Peat’s work
7:33 – how a low vitamin A diet can have benefits
9:27 – cautioning against the idea of "detox" as an excuse for negative effects and vitamin A toxicity as an unfalsifiable hypothesis
12:33 – the importance of evaluating information objectively while avoiding censorship, tribalism, fearmongering, and religiosity
21:17 – concerns with the current state of the Ray Peat Forum and how to recognize unsubstantiated claims
26:45 – Grant's initial critiques of the original studies on vitamin A deficiency are extremely weak and unsubstantiated
41:48 – introducing Wolbach’s 1925 study on vitamin A deficiency
45:47 – refuting Grant's argument that the retinoic acid in the vitamin-free casein would have caused toxicity
52:35 – refuting Grant's argument regarding confounding variables in lard and butter
1:02:53 – research on vitamin A deficiency and whether vitamin A deficiencies exist
1:20:32 – the necessity of vitamin A for pregnancy, fetal growth, and development
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-118-the-truth-about-serotonin-and-ssris-why-serotonin-is-not-the-happy-hormone
Timestamps:
0:00 – intro
0:58 – the research showing that serotonin is not the “happy hormone”
4:56 – serotonin’s role in driving the stress state that leads to depression
8:26 – the overlap between anxiety and depression and why they are both characterized by elevated serotonin levels
10:27 – the origins of the idea that serotonin is the “happy hormone” and how serotonin became a marketing tool for pharmaceutical companies
14:49 – serotonin is increased during fasting and starvation and why increasing serotonin should not be our goal
20:16 – serotonin is increased during stress, shock, and infection and leads to learned helplessness
29:04 –SSRIs use in neonates causes depression in adulthood
31:35 – the serotonergic system as an adaptive stress response to a lack of energy
39:09 – serotonin’s role in energy redistribution under stress
43:15 – how SSRIs inhibit mitochondrial respiration, glucose metabolism, and energy production in the brain and liver
47:13 – how SSRIs can reduce symptoms and how the brain responds to SSRIs
52:42 – the true drivers of depression and anxiety
1:01:30 – how serotonin relates to stress hormones, including cortisol, and energy balance
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-117-fructose-malabsorption-protecting-against-alcohol-and-brain-injuries-and-inflammation-q-and-a
Timestamps:
0:00 – intro
1:15 – how fructose gets absorbed in the small intestine
4:24 – the optimal fructose to glucose ratio and how to tell if you have fructose malabsorption
8:41 – the details of how glucose helps with fructose absorption
12:04 – which foods have a high fructose to glucose ratio
16:24 – issues with FODMAP categorization and whether fructose is really a FODMAP
21:23 – listening to your body and understanding individual context vs following rigid “food rules”
27:39 – anti-inflammatory diets and whether we should avoid sugar and supplement with fish oil to reduce brain inflammation
32:06 – dietary and supplement strategies to promote an anti-inflammatory state in the brain
39:15 – the effectiveness of red-light therapy, methylene blue, progesterone, exogenous ketones, and polyphenols in treating brain injuries
44:31 – why we don’t want to prioritize omega 3s in the diet and whether eating fish is any better than fish oil supplementation
47:21 – reducing inflammation with the use of aspirin
47:53 – the main concerns with drinking alcohol: intestinal permeability, endotoxin production, and liver health
52:32 – stress-relieving supplement alternatives to alcohol and the effects of alcohol on vitamins and minerals
54:37 – strategies to mitigate the effects of alcohol in the short-term
58:14 – whether it makes sense to drink alcohol, alcohol use as a coping mechanism, and the impact of culture
1:00:07 – more strategies for mitigating the effects of alcohol in the short and long term
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-116-the-truth-about-ldl-and-heart-disease-lmhr-and-the-lipid-energy-model/
Timestamps:
0:00 – intro
1:17 – the primary counterarguments against the Lipid Energy Model
4:15 – BMI, not saturated fat, correlates with the LMHR phenotype
8:15 – eating carbs dramatically lowers cholesterol in LMHR
11:14 – whether Oreos are more effective at lowering cholesterol than statins
17:30 – high cholesterol levels in the LMHR phenotype are not due to excess saturated fat intake or cholesterol production
19:25 – prominent cardiologists and researchers dismissing the lipid energy model due to dogmatism interferes with progress in science and medicine
24:40 – Dr. Shawn Baker’s carbohydrate experiment and contextual considerations when reintroducing carbs into the diet
28:46 – further support for the lipid energy model and the relationship with thyroid function
33:32 – the difference between saturated, monounsaturated, and polyunsaturated fats in relation to lipid profiles
34:40 – whether LDL cholesterol and ApoB cause heart disease and plaque formation
42:18 – how the Lipid Energy Model helps uncover the underlying cause of heart disease
45:15 – LDL levels as a marker of metabolic health rather than a cause of cardiovascular disease and why we may not always want to lower LDL
55:02 – evidence suggesting that LDL does not drive cardiovascular disease
1:05:43 – the difference between high LDL due to metabolic dysfunction and high LDL due to a low-carb diet
1:09:58 – lipid values don’t tell us the whole picture: the Kitavans
1:16:54 – why decreases in insulin, glucose, and HbA1C as well as increased lipolysis and fat oxidation on a low-carb diet is not necessarily a sign of improvement
1:22:57 – increased lipolysis on low-carb diets does not lead to body-fat loss
1:24:25 – whether the Lipid Energy Model proves that low-carb diets are optimal for health
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-115-lmhr-and-the-lipid-energy-model-implications-for-metabolism-and-hormones
Timestamps:
0:00 – intro
1:14 – what is the Lean Mass Hyper-Responder (LMHR) phenotype
3:33 – how the Lipid Energy Model challenges the mainstream dogmatic view linking high cholesterol levels to heart disease
6:33 – the protective effects of cholesterol and why it does not cause heart disease, despite being necessary for atherosclerosis
9:49 – the distinction between Lean Mass Hyper-Responders and those with high cholesterol levels in the context of metabolic dysfunction
15:10 – what is the Lipid Energy Model
22:10 – how the body adapts to a lack of carbohydrates, leading to elevated cholesterol levels
27:22 – the hormonal and metabolic state underlying the Lean Mass Hyper-Responder phenotype
32:21 – how adding carbohydrates lowers cholesterol levels in those who don't have metabolic dysfunction at a cellular level
37:11 – whether Lean Mass Hyper-Responders are at increased risk of cardiovascular disease
42:00 – why the Lean Mass Hyper-Responder phenotype isn't ideal: stress and low thyroid function
51:10 – the parallels between the lipid energy model and physiological insulin resistance
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-114-fat-burning-drives-insulin-resistance-and-eating-carbohydrates-improves-insulin-sensitivity/
Timestamps:
0:00 – intro
1:17 – stress hormones (glucagon, epinephrine, and cortisol) are major contributors to insulin resistance and diabetes
4:05 – elevated glucagon levels, not carbohydrates, are the driving force behind high fasting blood glucose levels
6:43 – glucagon is a driver of insulin resistance, while insulin is just a symptom
12:46 – the research showing that blocking stress hormones directly improves insulin sensitivity
15:14 – “hormetic” stressors like intermittent fasting, cause insulin resistance
19:30 – fat burning drives insulin resistance and keeps us in a catabolic state, driving weight gain and muscle wasting
22:15 – cortisol drives insulin resistance and why serum cortisol levels don’t provide the full picture
25:00 – low-carb diets reduce insulin sensitivity while carbohydrate intake improves it
29:40 – decreasing fatty acid oxidation by increasing carb intake improves our ability to tolerate carbohydrates
33:46 – burning fat contributes to increased disease processes and does not lead to losing more body fat
38:04 – fatty acid oxidation damages our mitochondria and increases fat storage
46:22 – type 2 diabetes directly contributes to heart disease by upregulating fatty acid oxidation
52:05 – how to decrease fatty acid oxidation and improve glucose metabolism
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-113-carbohydrates-dont-cause-insulin-resistance-or-diabetes-evidence-for-the-bioenergetic-view
Timestamps:
0:00 – intro
1:28 – what the mainstream view of insulin resistance gets wrong when it comes to what causes insulin resistance and diabetes
3:24 – glycolysis and fat oxidation are favored, and glucose oxidation is inhibited in insulin resistance and diabetes
8:39 – what happens to glucose in diabetic cells
10:32 – why insulin resistance is a symptom rather than the driver of diabetes
12:55 – research showing that insulin resistance is driven by poor glucose metabolism
20:50 – impaired glucose uptake is not caused by excess insulin; fat-burning and impaired glucose metabolism are the culprits
27:10 – the problems with relying on fat oxidation over carbohydrate oxidation
30:43 – how increasing blood glucose levels or increasing insulin can restore normal glucose uptake in diabetes
35:28 – how insulin actually lowers blood sugar and the effects of insulin on cortisol and other stress hormones
37:16 - why fatty acid oxidation is NOT the underlying cause of insulin resistance
40:06 – factors that support or block mitochondrial respiration
41:20 – how excess fatty acid oxidation contributes to the pathology of insulin resistance and can impair glucose metabolism over time
42:49 - how insulin actually lowers blood sugar and the effects of insulin on cortisol and other stress hormones (cont.)
47:08 – why we don’t want to blame insulin for insulin resistance and what really causes high fasting blood glucose
49:22 – how low-carb diets increase stress hormones and decrease insulin sensitivity
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-112-the-problems-with-resistant-starch-and-balancing-the-calcium-to-phosphorus-ratio-qa
Timestamps:
0:00 – intro
1:00 – mainstream health claims about resistant starch and why we disagree
6:15 – whether there are any benefits to including resistant starch in your diet
11:07 – how to tell if resistant starch is negatively impacting your gut health and how to avoid it
16:05 – which starches are easiest to digest and the factors that affect our ability to digest starches optimally
21:38 – why we should pay attention to our calcium to phosphorus ratio and the risks of high parathyroid hormone levels
26:19 – the optimal calcium to phosphorus ratio and the calcium paradox in terms of regulating blood pressure
31:21 – which phosphorus-containing foods we should avoid to optimize bone density
34:36 – the calcium paradox and why consuming calcium doesn’t increase intracellular calcium
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-111-stevia-vs-sugar-ketogenic-diets-for-epilepsy-and-spore-based-vs-standard-probiotics-qa
Timestamps:
0:00 – intro
1:17 – whether spore-based probiotics can cause bacterial overgrowths like SIBO
4:53 – the drawbacks of standard probiotic use and the limitations of stool testing
9:55 – how spore-based probiotics protect against pathogenic bacteria and endotoxin and which spore-based product Jay recommends
15:39 – long-term benefits of spore-based probiotics and how long you need to use them for these benefits
21:05 – whether low-carb or ketogenic diets are necessary to improve epilepsy
29:25 – using ketones for fuel and why the production of ketones isn't the problem on a ketogenic diet
30:48 – the main drivers of epileptic seizures and how ketones help to prevent or reverse them
34:17 – the role of the gut microbiome in brain health and epilepsy
42:18 – concerns with low- or no-calorie sweeteners like stevia
48:03 – whether we should be concerned about the lack of nutrients in table sugar, honey, and maple syrup
54:55 – stevia as a potential endocrine disruptor that may have negative effects on the thyroid, liver, and kidneys
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-110-the-true-cause-of-insulin-resistance-and-diabetes-from-the-bioenergetic-view/
Timestamps:
0:00 – intro
1:14 – metabolic flexibility, earning your carbs, the carb-insulin model of obesity, and dispelling other common insulin resistance myths
7:48 – low-carb, keto, and carnivore diets may improve symptoms but are not the solution for insulin resistance
13:13 – what the mainstream views of insulin resistance gets wrong when it comes to what causes insulin resistance
15:50 – why you might not want to use a continuous glucose monitor and the unnecessary fear of blood glucose spikes
17:48 – whether insulin is harmful and whether we want to keep insulin levels as low as possible
22:15 – whether we can restore optimal insulin sensitivity without low-carb diets
25:16 –the bioenergetic view of insulin resistance
27:12 – insulin resistance as an adaptive evolutionary process that is crucial for survival
31:22 – the difference between physiological and pathological insulin resistance
34:40 – how inhibited glucose oxidation causes insulin resistance
40:46 – how fatty acid oxidation causes increased production of ROS, slows cellular respiration, and blocks glucose oxidation (The Randle Cycle)
51:06 – the harms of ROS production from fatty acid oxidation and other forms of stress
53:04 – insulin resistance as an energy deficient state
54:19 – insulin resistance is not an insulin signaling problem, it’s an energy production problem
58:30 – the role of stress hormones (like cortisol) in insulin resistance
1:02:09 – how insulin and carbohydrates decrease stress
1:05:59 – how to fix insulin resistance and restore insulin sensitivity by fixing our capacity to produce energy
1:10:38 – specific diet, movement, and supplementation recommendations for insulin resistance and diabetes
1:17:55 – why you don’t need to tailor your carb intake to your carb tolerance
The podcast currently has 120 episodes available.
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