Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Click here to check out the show notes:

Timestamps:

0:00 – intro 

1:06 – is there a daily limit to how much oxalate the kidneys can process? 

9:26 – whether we automatically store oxalates if they aren’t cleared through the kidneys 

13:40 – why mitochondrial function in the kidney is crucial for calcium oxalate crystal clearance 

17:30 – the benefits of citrate and whether it’s effective for clearing oxalates 

23:30 – whether baking soda (sodium bicarbonate) support the clearance of oxalates 

27:05 – how pH balance relates to oxalate clearance 

32:19 – is “oxalate dumping” real? 

43:06 – how low-carb diets increase oxalate absorption 

47:19 – whether having a small amount of oxalates helps prevent oxalate dumping 

50:02 – how low-carb diets increase oxalate absorption (cont.) 

52:19 – why low-carb diets like keto and carnivore may increase oxalate production relative to high-carb diets 

1:00:42 – how high-protein diets lead to increased endogenous oxalate production 

1:07:41 – how carbohydrates and insulin reduce oxidative stress and oxalate production 

1:11:40 – why glucose does not cause the formation of advanced glycation end products 

1:13:18 – how low-carb diets reduce oxalate clearance – stressed kidneys, lack of citrate intake, and more acidic blood & urine

Kitty's Instagram: https://www.instagram.com/kittyblomfield/?hl=en

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro 

0:38– how Kitty got introduced to Ray Peat 

3:59 – whether intermittent fasting is beneficial for women 

9:07 – the appeal of intermittent fasting and other restrictive diets, and why they do more harm than good 

14:41 – the truth about body recomposition: women are underfed and lack muscle 

17:29 – why low-carb diets like keto and carnivore are not sustainable 

19:36 – how mainstream health advice has ruined our diets and why we should eat like our grandparents 

25:21 – the role of stress in digestive health and the problem with jumping to supplements 

31:12 – when it makes sense to move on to more advanced health strategies such as lab testing, hormone replacement therapy, or gut protocols 

38:30 – Is Being Fat a Choice? Middle Ground by Jubilee 

41:23 – the relationship between emotional trauma, body image issues, and physical healing 

44:16 – what really influences body weight? 

53:30 – the importance of enjoying the food you eat daily and how it helps prevent binge eating 

55:25 – whether we should drink tons of water first thing in the morning 

57:35 – how much water do we really need? 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Click here to check out the show notes:

Timestamps:

0:00 – intro 

1:12 – overview of endogenous vs. exogenous oxalates 

5:46 – how much oxalate comes from endogenous production vs. diet 

9:14 – when endogenous oxalate production matters more than dietary oxalate 

15:03 – rare genetic disorders that cause excessive oxalate production: primary hyperoxaluria 

22:36 – the pathways in the liver that lead to oxalate production 

32:41 – other biochemical pathways involved in endogenous oxalate production 

41:19 – deranged metabolic function as a primary driver of glyoxal production and lipid peroxidation 

45:14 – the extent to which glycine and vitamin C contribute to endogenous oxalate formation 

48:00 – how much does hydroxyproline contribute to oxalate production? 

52:06 – the primary precursor to oxalate that’s often ignored (glyoxal) 

55:08 – how oxidative stress drives oxalate production and how antioxidants help 

1:01:20 – what causes the high oxalate levels seen in type 2 diabetes, obesity, cardiovascular disease, and non-alcoholic fatty liver disease (NAFLD)? 

1:11:16 – the protective effects of glycine in states of excess oxalate production 

1:15:54 – elevated stress hormones and gluconeogenesis increase oxalate production 

1:22:43 – nutrient deficiencies that contribute to oxalate issues (vitamin B1, vitamin B6, and zinc)

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

0:48 – Peter Attia admits he was wrong about fasting after 10 years of muscle loss 

4:00 – the importance of critical thinking and whether it's okay to change your mind 

11:46 – why experimentation should be guided by sound logic 

18:06 – whether supplementing with BCAAs (branched-chain amino acids) while fasting prevents muscle loss 

20:58 – the long-term cost of fasting and relying on adrenaline for energy and focus: impaired cognition, thyroid, testosterone, digestion, and more 

30:19 – Peter Attia says there’s no benefit to fasting beyond calorie restriction – is reduced protein intake the only drawback? 

38:34 – the problems with traditional education, where memorization replaces true learning 

41:03 – whether fasting is optimal because our ancestors fasted 

45:32 – whether evolution is purely random and whether we should mimic our ancestors 

51:58 – the cumulative effects of fasting and high stress hormones (anxiety, insomnia, low body temperature, weakened immune function) 

54:09 – whether methionine restriction is recommended to increase lifespan 

1:03:08 – the importance of consuming more gelatinous, collagen rich cuts of meats  

1:06:03 – the benefits and possible drawbacks of supplementing with glycine and taurine 

1: 10:53 – how to properly use taurine for bile acid stimulation 

1:16:33 – Anthony Chaffee disagrees with Paul Saladino on fructose – is fructose just alcohol without the buzz? 

1:23:11 – whether fructose is broken down into the same byproducts as alcohol 

1:30:01 – the difference between fructose and alcohol metabolism in the liver 

1:35:10 – whether fructose increases de novo lipogenesis and contributes to fatty liver disease 

1:44:43 – the problems with trusting medical advice based on appearance and authoritative stance, and how to discern credible sources 

1:51:04 – critiquing Paul Saladino’s take on the benefits of nitric oxide 

1:55:43 – the cost of organ transplants 

1:57:32 – optimizing gut motility, relieving constipation, and how fiber can help with protein and fat digestion 

2:04:03 – how dining out at restaurants can hinder progress and impede healing 

2:08:30 – how even high-end restaurants use toxic cooking oils and reasons to avoid aged meat 

2:12:44 – strategies for avoiding toxic foods in social settings and while traveling 

Whether the harmful effects of oxalates are legitimate or overblown

How your gut health impacts your susceptibility to oxalate issues

Which nutrients help decrease oxalate absorption

How fat digestion relates to oxalate absorption

Whether a candida overgrowth may be at the root of your oxalate issues

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-128-are-oxalates-the-problem-or-is-it-your-gut/

Timestamps:

0:00 – intro 

1:08 – common misconceptions about oxalates and whether oxalate concerns are justified

5:21 – symptoms often attributed to oxalates and whether they are truly responsible for most health problems

12:48 – what are oxalates? 

16:18 – oxalates cause kidney damage and reduce mineral bioavailability

21:34 – oxalates and cardiovascular disease

24:43 – oxalates as a driver of gut dysbiosis and decreased bile acid production

29:16 – metabolic damage caused by oxalates

37:06 – how a low-PUFA diet and vitamin E can protect against oxalate damage

43:19 – high oxalate foods and factors that impact oxalate absorption

53:29 – soluble vs. insoluble oxalates

57:04 – how calcium affects oxalate absorption and the impact of parathyroid hormone and 1,25-Dihydroxyvitamin D

1:07:41 – the effects of magnesium on oxalate absorption

1:12:44 – how deficiencies in vitamin B1 (thiamine) and vitamin B6 can increase oxalate levels

1:14:44 – how gut health relates to oxalate issues (fat digestion, intestinal permeability, and oxalate degrading bacteria)

1:22:23 – “oxalate dumping” on low-carb diets and carnivore diets may be due to poor gut health

1:26:15 – whether candida infections or other fungal infections cause excess oxalate production

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

1:46 – Gabrielle Lyon promotes bro science: 1 gram of protein per pound of bodyweight 

7:15 – problems with high-protein diets – stress hormones, low testosterone, slowed metabolism, and gut toxins

15:21 – whether studies on Eskimo and Inuit populations support a high-protein diet

16:59 – the problems with Gabrielle Lyon’s recommendation of a 1:1 protein to carbohydrate ratio

23:48 – the minimum amount of carbs we need daily and the consequences of not getting enough

26:56 – Gabrielle Lyon is confused about fats

35:43 – types of fats commonly used in bodybuilding and whether they’re truly optimal

37:37 – Dr Boz’s recommendations for high blood sugar on carnivore and OMAD (one-meal-a-day)

45:59 – the drivers of high fasting blood glucose on low-carb diets

49:38 – whether overeating is really an issue on the carnivore diet and why increased appetite signals improved health

57:28 – whether Dr. Boz's recommendation to shift the eating window earlier has any validity

1:01:33 – Sean Baker’s shift away from the carnivore diet

1:03:31 –Dr Boz denies that the carnivore diet caused increased fasting blood sugar

1:11:16 – why Dr Berg is wrong – serotonin is not the “happy hormone”

1:20:40 – the idea that low serotonin causes depression and high serotonin reverses it is unsupported

1:23:05 – our thoughts on Dr. Berg's recommendations for raising serotonin: exercise, fasting, and tryptophan

1:28:46 – whether vitamin D increases serotonin

1:30:56 – the benefits of sunlight and red-light exposure

1:39:39 –the problems with Glucose Goddess’s strategies to prevent blood glucose spikes

1:49:22 – insulin and blood sugar spikes are misunderstood

1:54:46 – how an excessive focus on blood glucose and insulin misses the underlying issues

1:55:59 – is obesity primarily caused by genetics?

2:01:49 – whether diet and exercise impact obesity rates

2:09:26 – the vital importance of finding fulfillment in life, following our passions, and escaping the grind of the rat race

2:15:12 – what it really takes to be healthy and whether it's possible to improve your health without expensive interventions

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-127-lipolysis-and-fat-loss-lose-body-fat-without-increasing-fat-burning/

Timestamps:

0:00 – intro

1:08 – the fat loss narrative: release more fat from your fat stores through intense exercise, fasting, cold plunges, and low-carb diets

4:08 – how fat gets released from our fat stores

8:40 – the baseline rate of fat release from our fat stores and the impact of degenerative states like cancer on lipolysis

12:09 – how fat is released from our fat stores in response to stressors like exercise

15:34 – the connection between lipolysis, metabolic syndrome, and fatty liver disease

23:29 – the research showing that decreasing lipolysis leads to less body fat (not more)

33:47 – whether we want to block hormone-sensitive lipase (HSL) activity

37:47 – the research showing that increasing fat burning and lipolysis does not increase fat loss

44:25 – how to lose body fat without relying on stress-driven fat oxidation

49:56 – strategies for fat loss without increased lipolysis: are exercise, fasting, and cold plunges the solution?

Analyze & Optimize's Website: https://www.analyzeandoptimize.io/

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro 

0:38 – how Analyze & Optimize (Jack & Dalton) got introduced to work of Ray Peat 

6:32 – how Analyze & Optimize create their videos 

10:40 – refuting Robert Lustig's claims – is fructose as harmful to the liver as alcohol? 

17:40 – whether Analyze & Optimize are paid by “big sugar”  

20:30 – Robert Lustig’s fructose claims are unsupported 

28:06 – is white sugar safe to consume? 

33:04 – Serotonin & Hierarchy by Jordan Peterson 

34:33 – SSRI use and serotonin’s role in promoting learned helplessness and anhedonia 

40:46 – how the perceived benefits of serotonin could be attributed to other factors 

45:45 – whether serotonin is the “dominance” hormone 

47:17 – Analyze & Optimize respond to Shawn Baker on sugar cravings being a sign of health and youth 

51:04 – declining health on the carnivore diet, whether it’s sustainable, and why your immune system needs carbohydrates 

54:04 – carnivore diet effects on gut health – quorum sensing, biofilms, high stress hormones, and damage to thyroid health 

1:01:30 – why chronic low-calorie intake turns down metabolic function and leads to obesity 

1:07:00 – the harm caused by conflating progesterone and synthetic progestins 

1:14:57 – the link between birth control and cancer and the protective effects of progesterone 

1:18:20 – the negative effects of synthetic progestins and estrogen, especially unchecked by natural progesterone 

1:24:45 – Why Is the Right So Obsessed with Seed Oils? by Ej Dickson 

1:31:15 – Dave Asprey argues with Paul Saladino on supplements vs orange juice 

1:39:10 – whether Ray Peat’s ideas and principles promote orthorexia 

1:44:22 – using precision medicine vs. listening to your body 

1:51:09 – where to find more of Jack & Dalton’s work 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-126-high-triglycerides-on-a-high-carb-diet-should-you-be-worried/

Timestamps:

0:00 – intro

1:10 – whether elevated triglycerides on a high-carbohydrate diet warrant concern 

3:21 – the association between LDL, cardiovascular disease, and metabolic syndrome 

5:52 – the lipid energy model and what accounts for the lipid values seen in Lean Mass Hyper-Responders (LMHR)  

9:26 – what causes higher triglycerides seen on higher-carb, lower-fat diets in someone who is insulin sensitive 

11:39 - what causes high triglycerides in insulin resistance 

18:08 – are elevated triglyceride levels on a high-carb diet concerning, and do they drive cardiovascular disease? 

24:08 – whether small, dense LDL and low HDL levels drive heart disease 

28:25 – native cultures showing high triglycerides on a high-carb diet with no signs of cardiovascular disease:Tarahumaras, Tukisenta, and the Kitavans 

34:10 – high-carb diets support insulin sensitivity and don’t increase uric acid levels in the Tukisenta  

37:23 –high-carb diets support insulin sensitivity without increased activity levels in the Kitavans 

43:43 – when elevated triglycerides might become a concern after increasing carbohydrate intake 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

0:28 – Andrew Huberman and Layne Norton on whether seed oils are inherently harmful

4:18 – why Layne Norton's "calories-only" view is flawed, as it ignores how the type of food actually affects our bodies

9:58 – whether animal studies are useful in nutritional research, or if only human randomized control trials (RTC) should be considered

15:57 – problematic assumptions and biases in nutritional research and how they can shape research outcomes

20:59 – why the reported health benefits of polyunsaturated fats in research are misleading and harmful

26:54 – the connection between chronic disease and polyunsaturated fats, and how focusing solely on calories relieves the food industry of responsibility for health outcomes

31:43 – Liver King's self-esteem, body image struggles, steroid use, health risks, and why his apology was commendable

41:36 – why cultural standards for physical appearances are unrealistic, unhealthy, and can lead to conflating steroid-enhanced bodies for genuine health

51:12 – health risks associated with steroid-use and having too much muscle mass

1:00:34 – Thomas Delauer and Derek from moreplatesmoredates discuss omega-3s

1:06:21 – whether the antioxidants in fish oil are worth the damage caused by lipid peroxidation

1:10:54 – whether cod liver oil is any better than fish oil

1:17:11 – how to effectively hydrate your cells and the importance of getting enough salt

1:24:44 – why consuming a lot of plain water without electrolytes actually impairs hydration, contributing to increased swelling, increased stress, and impaired energy production

1:32:38 – the importance of getting adequate potassium in addition to salt intake

1:38:03 – factors that may increase your need for water

1:40:02 – what Ben Bikman misses when it comes to blood glucose and insulin resistance

1:48:15 – the true relationship between insulin and blood sugar regulation

1:54:30 – Ben Bikman misapplies this study: it does not support that carbohydrates cause insulin resistance

2:00:38 – creating content in the health sphere, choosing high quality foods, and the benefits of tracking food (using Cronometer or another similar app)