Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

0:48 – Peter Attia admits he was wrong about fasting after 10 years of muscle loss 

4:00 – the importance of critical thinking and whether it's okay to change your mind 

11:46 – why experimentation should be guided by sound logic 

18:06 – whether supplementing with BCAAs (branched-chain amino acids) while fasting prevents muscle loss 

20:58 – the long-term cost of fasting and relying on adrenaline for energy and focus: impaired cognition, thyroid, testosterone, digestion, and more 

30:19 – Peter Attia says there’s no benefit to fasting beyond calorie restriction – is reduced protein intake the only drawback? 

38:34 – the problems with traditional education, where memorization replaces true learning 

41:03 – whether fasting is optimal because our ancestors fasted 

45:32 – whether evolution is purely random and whether we should mimic our ancestors 

51:58 – the cumulative effects of fasting and high stress hormones (anxiety, insomnia, low body temperature, weakened immune function) 

54:09 – whether methionine restriction is recommended to increase lifespan 

1:03:08 – the importance of consuming more gelatinous, collagen rich cuts of meats  

1:06:03 – the benefits and possible drawbacks of supplementing with glycine and taurine 

1: 10:53 – how to properly use taurine for bile acid stimulation 

1:16:33 – Anthony Chaffee disagrees with Paul Saladino on fructose – is fructose just alcohol without the buzz? 

1:23:11 – whether fructose is broken down into the same byproducts as alcohol 

1:30:01 – the difference between fructose and alcohol metabolism in the liver 

1:35:10 – whether fructose increases de novo lipogenesis and contributes to fatty liver disease 

1:44:43 – the problems with trusting medical advice based on appearance and authoritative stance, and how to discern credible sources 

1:51:04 – critiquing Paul Saladino’s take on the benefits of nitric oxide 

1:55:43 – the cost of organ transplants 

1:57:32 – optimizing gut motility, relieving constipation, and how fiber can help with protein and fat digestion 

2:04:03 – how dining out at restaurants can hinder progress and impede healing 

2:08:30 – how even high-end restaurants use toxic cooking oils and reasons to avoid aged meat 

2:12:44 – strategies for avoiding toxic foods in social settings and while traveling 

Whether the harmful effects of oxalates are legitimate or overblown

How your gut health impacts your susceptibility to oxalate issues

Which nutrients help decrease oxalate absorption

How fat digestion relates to oxalate absorption

Whether a candida overgrowth may be at the root of your oxalate issues

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-128-are-oxalates-the-problem-or-is-it-your-gut/

Timestamps:

0:00 – intro 

1:08 – common misconceptions about oxalates and whether oxalate concerns are justified

5:21 – symptoms often attributed to oxalates and whether they are truly responsible for most health problems

12:48 – what are oxalates? 

16:18 – oxalates cause kidney damage and reduce mineral bioavailability

21:34 – oxalates and cardiovascular disease

24:43 – oxalates as a driver of gut dysbiosis and decreased bile acid production

29:16 – metabolic damage caused by oxalates

37:06 – how a low-PUFA diet and vitamin E can protect against oxalate damage

43:19 – high oxalate foods and factors that impact oxalate absorption

53:29 – soluble vs. insoluble oxalates

57:04 – how calcium affects oxalate absorption and the impact of parathyroid hormone and 1,25-Dihydroxyvitamin D

1:07:41 – the effects of magnesium on oxalate absorption

1:12:44 – how deficiencies in vitamin B1 (thiamine) and vitamin B6 can increase oxalate levels

1:14:44 – how gut health relates to oxalate issues (fat digestion, intestinal permeability, and oxalate degrading bacteria)

1:22:23 – “oxalate dumping” on low-carb diets and carnivore diets may be due to poor gut health

1:26:15 – whether candida infections or other fungal infections cause excess oxalate production

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

1:46 – Gabrielle Lyon promotes bro science: 1 gram of protein per pound of bodyweight 

7:15 – problems with high-protein diets – stress hormones, low testosterone, slowed metabolism, and gut toxins

15:21 – whether studies on Eskimo and Inuit populations support a high-protein diet

16:59 – the problems with Gabrielle Lyon’s recommendation of a 1:1 protein to carbohydrate ratio

23:48 – the minimum amount of carbs we need daily and the consequences of not getting enough

26:56 – Gabrielle Lyon is confused about fats

35:43 – types of fats commonly used in bodybuilding and whether they’re truly optimal

37:37 – Dr Boz’s recommendations for high blood sugar on carnivore and OMAD (one-meal-a-day)

45:59 – the drivers of high fasting blood glucose on low-carb diets

49:38 – whether overeating is really an issue on the carnivore diet and why increased appetite signals improved health

57:28 – whether Dr. Boz's recommendation to shift the eating window earlier has any validity

1:01:33 – Sean Baker’s shift away from the carnivore diet

1:03:31 –Dr Boz denies that the carnivore diet caused increased fasting blood sugar

1:11:16 – why Dr Berg is wrong – serotonin is not the “happy hormone”

1:20:40 – the idea that low serotonin causes depression and high serotonin reverses it is unsupported

1:23:05 – our thoughts on Dr. Berg's recommendations for raising serotonin: exercise, fasting, and tryptophan

1:28:46 – whether vitamin D increases serotonin

1:30:56 – the benefits of sunlight and red-light exposure

1:39:39 –the problems with Glucose Goddess’s strategies to prevent blood glucose spikes

1:49:22 – insulin and blood sugar spikes are misunderstood

1:54:46 – how an excessive focus on blood glucose and insulin misses the underlying issues

1:55:59 – is obesity primarily caused by genetics?

2:01:49 – whether diet and exercise impact obesity rates

2:09:26 – the vital importance of finding fulfillment in life, following our passions, and escaping the grind of the rat race

2:15:12 – what it really takes to be healthy and whether it's possible to improve your health without expensive interventions

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-127-lipolysis-and-fat-loss-lose-body-fat-without-increasing-fat-burning/

Timestamps:

0:00 – intro

1:08 – the fat loss narrative: release more fat from your fat stores through intense exercise, fasting, cold plunges, and low-carb diets

4:08 – how fat gets released from our fat stores

8:40 – the baseline rate of fat release from our fat stores and the impact of degenerative states like cancer on lipolysis

12:09 – how fat is released from our fat stores in response to stressors like exercise

15:34 – the connection between lipolysis, metabolic syndrome, and fatty liver disease

23:29 – the research showing that decreasing lipolysis leads to less body fat (not more)

33:47 – whether we want to block hormone-sensitive lipase (HSL) activity

37:47 – the research showing that increasing fat burning and lipolysis does not increase fat loss

44:25 – how to lose body fat without relying on stress-driven fat oxidation

49:56 – strategies for fat loss without increased lipolysis: are exercise, fasting, and cold plunges the solution?

Analyze & Optimize's Website: https://www.analyzeandoptimize.io/

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro 

0:38 – how Analyze & Optimize (Jack & Dalton) got introduced to work of Ray Peat 

6:32 – how Analyze & Optimize create their videos 

10:40 – refuting Robert Lustig's claims – is fructose as harmful to the liver as alcohol? 

17:40 – whether Analyze & Optimize are paid by “big sugar”  

20:30 – Robert Lustig’s fructose claims are unsupported 

28:06 – is white sugar safe to consume? 

33:04 – Serotonin & Hierarchy by Jordan Peterson 

34:33 – SSRI use and serotonin’s role in promoting learned helplessness and anhedonia 

40:46 – how the perceived benefits of serotonin could be attributed to other factors 

45:45 – whether serotonin is the “dominance” hormone 

47:17 – Analyze & Optimize respond to Shawn Baker on sugar cravings being a sign of health and youth 

51:04 – declining health on the carnivore diet, whether it’s sustainable, and why your immune system needs carbohydrates 

54:04 – carnivore diet effects on gut health – quorum sensing, biofilms, high stress hormones, and damage to thyroid health 

1:01:30 – why chronic low-calorie intake turns down metabolic function and leads to obesity 

1:07:00 – the harm caused by conflating progesterone and synthetic progestins 

1:14:57 – the link between birth control and cancer and the protective effects of progesterone 

1:18:20 – the negative effects of synthetic progestins and estrogen, especially unchecked by natural progesterone 

1:24:45 – Why Is the Right So Obsessed with Seed Oils? by Ej Dickson 

1:31:15 – Dave Asprey argues with Paul Saladino on supplements vs orange juice 

1:39:10 – whether Ray Peat’s ideas and principles promote orthorexia 

1:44:22 – using precision medicine vs. listening to your body 

1:51:09 – where to find more of Jack & Dalton’s work 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-126-high-triglycerides-on-a-high-carb-diet-should-you-be-worried/

Timestamps:

0:00 – intro

1:10 – whether elevated triglycerides on a high-carbohydrate diet warrant concern 

3:21 – the association between LDL, cardiovascular disease, and metabolic syndrome 

5:52 – the lipid energy model and what accounts for the lipid values seen in Lean Mass Hyper-Responders (LMHR)  

9:26 – what causes higher triglycerides seen on higher-carb, lower-fat diets in someone who is insulin sensitive 

11:39 - what causes high triglycerides in insulin resistance 

18:08 – are elevated triglyceride levels on a high-carb diet concerning, and do they drive cardiovascular disease? 

24:08 – whether small, dense LDL and low HDL levels drive heart disease 

28:25 – native cultures showing high triglycerides on a high-carb diet with no signs of cardiovascular disease:Tarahumaras, Tukisenta, and the Kitavans 

34:10 – high-carb diets support insulin sensitivity and don’t increase uric acid levels in the Tukisenta  

37:23 –high-carb diets support insulin sensitivity without increased activity levels in the Kitavans 

43:43 – when elevated triglycerides might become a concern after increasing carbohydrate intake 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Timestamps:

0:00 – intro

0:28 – Andrew Huberman and Layne Norton on whether seed oils are inherently harmful

4:18 – why Layne Norton's "calories-only" view is flawed, as it ignores how the type of food actually affects our bodies

9:58 – whether animal studies are useful in nutritional research, or if only human randomized control trials (RTC) should be considered

15:57 – problematic assumptions and biases in nutritional research and how they can shape research outcomes

20:59 – why the reported health benefits of polyunsaturated fats in research are misleading and harmful

26:54 – the connection between chronic disease and polyunsaturated fats, and how focusing solely on calories relieves the food industry of responsibility for health outcomes

31:43 – Liver King's self-esteem, body image struggles, steroid use, health risks, and why his apology was commendable

41:36 – why cultural standards for physical appearances are unrealistic, unhealthy, and can lead to conflating steroid-enhanced bodies for genuine health

51:12 – health risks associated with steroid-use and having too much muscle mass

1:00:34 – Thomas Delauer and Derek from moreplatesmoredates discuss omega-3s

1:06:21 – whether the antioxidants in fish oil are worth the damage caused by lipid peroxidation

1:10:54 – whether cod liver oil is any better than fish oil

1:17:11 – how to effectively hydrate your cells and the importance of getting enough salt

1:24:44 – why consuming a lot of plain water without electrolytes actually impairs hydration, contributing to increased swelling, increased stress, and impaired energy production

1:32:38 – the importance of getting adequate potassium in addition to salt intake

1:38:03 – factors that may increase your need for water

1:40:02 – what Ben Bikman misses when it comes to blood glucose and insulin resistance

1:48:15 – the true relationship between insulin and blood sugar regulation

1:54:30 – Ben Bikman misapplies this study: it does not support that carbohydrates cause insulin resistance

2:00:38 – creating content in the health sphere, choosing high quality foods, and the benefits of tracking food (using Cronometer or another similar app)

In this episode we discuss:

• Whether estrogen is just a reproductive hormone

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-124-forget-about-cico-a-smarter-approach-to-fat-loss/

Timestamps:

0:00 – intro 

1:07 – our thoughts on Wendy Sellens’ recent interviews with the Strong Sistas (Ashley and Sarah Armstrong) 

6:30 – the importance of reviewing research with an open mind, avoiding any rigid or authoritative stance 

9:38 – whether all research should be rejected due to Rockefeller funding and whether Dr Ray Peat was “Rockefeller trained” 

15:47 – whether reproductive hormones affect only reproductive organs 

20:35 – how hormonal imbalances affect all areas of health—reproduction, digestion, edema, bloating, cancer risk, weight gain, brain health, bone health, and muscle growth 

23:38 – whether Dr Hobbins’ experiments proved that there are no receptors for reproductive hormones in non-reproductive organs 

26:51 – why Wendy’s claim—that the rise in estrogen during pregnancy is caused by exogenous compounds (phytoestrogens and xenoestrogens)—is incorrect 

29:29 – estrogen’s role as a growth-promoting hormone and how progesterone counterbalances it by promoting cellular differentiation 

35:47 – whether testosterone can be converted into estrogen 

36:52 – how you can have excess estrogen production even after menopause and problems with estrogen testing 

40:19 – body fat as a major source of estrogen 

44:33 – why Wendy’s claim that calcium D-glucarate increases estrogen is incorrect 

46:56 – the mechanism through which calcium D-glucarate effectively lowers estrogen levels 

50:28 – confounding variables that make it difficult to accurately interpret the results of breast thermography scans 

In this episode we discuss:

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Danny's Telegram: https://t.me/dannyroddy

Timestamps:

0:00 – intro

1:10 – whether estrogen is a carcinogen 

6:13 – estrogen’s role in driving weight gain and chronic diseases such as cancer, Alzheimer’s disease, and Type 2 Diabetes 

8:03 – the dangers of synthetic progesterone (progestin) use 

10:14 – the difference between estrone and estradiol and the problems with estrogen testing 

16:14 – whether estrogen therapy should be used in post-menopausal women 

17:17 – the difference between oral and transdermal estrogen use 

24:44 – the connection between inflammation and estrogen production 

27:57 – why estrogen levels are not actually low in post-menopausal women 

37:59 – our take on Siim Land's post on NAD+ and mitochondrial uncoupling 

48:25 – why intentionally seeking hormetic responses, like the activation of heat-shock proteins, should be avoided 

50:37 – which form of CoQ10 is better: ubiquinone or ubiquinol 

53:34 – what Siim Land and many others get wrong when it comes to raising NAD+  

55:44 – does fasting and AMPK upregulation cause cancer? 

1:00:29 – fat fuels cancer and why not to restrict sugar for cancer 

1:09:56 – Dr Berg’s take that serotonin is the “happy hormone” – why we disagree 

1:19:06 – serotonin’s role in driving chronic diseases and conditions including depression, anxiety, IBS, and cancer 

1:27:24 – Nutrition with Judy claims that the low thyroid levels generally seen on the carnivore diet have nothing to do with a lack of carbohydrates 

1:39:01 – how the rate of living theory changed mainstream medicine’s view that thyroid health is important 

1:45:37 – how excessive exercise raises stress hormones, setting you up for weight regain 

1:51:30 – why the combination of fasting and exercise is detrimental to our health 

1:53:44 – how estrogen is used to fatten animals  

2:02:42 – why Dave Asprey is talking about endotoxin and orange juice 

2:07:00 – whether the sugar in orange juice feeds bacteria and increases endotoxin 

2:09:40 – why the low-carb trend keeps resurfacing, despite the growing evidence against it 

2:14:41 – where to find Georgi and IdeaLabs 

In this episode we discuss:

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-124-forget-about-cico-a-smarter-approach-to-fat-loss/

Timestamps:

0:00 – intro

1:06 – recapping the problems with CICO

5:02 – the Energy Balance approach as an alternative to CICO for fat loss

12:12 – why calories do not equal energy and considering the possible fates of the food we consume

17:39 – efficient mitochondrial function as a central piece that determines whether substrate will be stored as body fat

19:39 – the amount of food you eat does matter

21:46 – conceptualizing Energy Balance with numerical units

24:00 – fat gain as a consequence of impaired mitochondrial function

29:01 – how you can lose fat while eating more

33:12 – the effects of energy availability on hunger and stress hormones

36:41 – how stress hormones, along with energy deficits, cause the body to break down muscle, bone, and skin for energy

43:16 – the benefits of having an energy surplus: improved sleep, immune function, digestion, cognitive function, and more

46:20 – comparing the Energy Balance approach with CICO and the major cost of the advice to “eat less and exercise more