Optimal Protein Podcast with Vanessa Spina

Rapid Fat Loss Without Muscle Loss? The Science on Protein-Sparing Modified Fasts (PSMF)


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This episode of the Optimal Protein Podcast takes a deep dive into the Protein-Sparing Modified Fast (PSMF) — a scientifically designed approach for rapid fat loss that prioritizes lean muscle preservation.

Listeners will learn:

  • What defines a PSMF and how it works in practice
  • The latest research on fat loss outcomes and muscle retention
  • How PSMF compares with ketogenic diets, VLCDs, and intermittent fasting
  • Differences in results between men and women
  • Short-term benefits and potential challenges with long-term use
  • How to implement cycling strategies, refeed phases, and sustainable maintenance plans
  • Evidence-based guidelines for safe and effective use

Packed with research findings and practical insights, this episode provides a clear, evidence-based look at how PSMF can be used as a tool for body recomposition, fat loss, and long-term health.

Connect with Vanessa on Instagram @ketogenicgirl

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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

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Optimal Protein Podcast with Vanessa SpinaBy Vanessa Spina

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