In this episode of the podcast, Dr. Whitney Jones, Grail's Senior Medical Advisor, joins us to discuss the Galleri cancer screening test. The Galleri test is a first-of-its-kind multi-cancer early detection test that can detect a signal shared by more than 50 cancer types and predict the tissue type or organ associated with the signal to help healthcare providers determine next steps.

The Galleri test is intended to complement routine single cancer screenings for more comprehensive early cancer detection. Routine screenings are recommended for certain patients for breast, cervical, colorectal, lung and prostate cancers.

Only screening for a single cancer does not effectively address the high prevalence of cancer given the probability of diagnosis for a specific cancer is uncertain, and the occurrence of individual cancers is relatively low. One in two men and one in three women are diagnosed with some form of cancer in America in their lifetime.

Some of the cancers that the Galleri test screens for include:

Adrenal Cortical Carcinoma

Ampulla of Vater

Anus

Appendix, Carcinoma

Bile Ducts, Distal

Bile Ducts, Intrahepatic

Bile Ducts, Perihilar

Bladder, Urinary

Bone

Breast

Cervix

Colon and Rectum

Esophagus and Esophagogastric Junction

Gallbladder

Gastrointestinal Stromal Tumor

Gestational Trophoblastic Neoplasms

Kidney

Larynx

Leukemia

Liver

Lung

Lymphoma (Hodgkin and Non-Hodgkin)

Melanoma of the Skin

Merkel Cell Carcinoma

Mesothelioma, Malignant Pleural

Nasal Cavity and Paranasal Sinuses Nasopharynx

Neuroendocrine Tumors of the Appendix

Neuroendocrine Tumors of the Colon and Rectum

Neuroendocrine Tumors of the Pancreas

Oral Cavity

Oropharynx (HPV-Mediated, p16+)

Oropharynx (p16-) and Hypopharynx

Ovary, Fallopian Tube and Primary Peritoneum

Pancreas, exocrine

Penis

Plasma Cell Myeloma and Plasma Cell Disorders

Prostate

Small Intestine

Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs

Soft Tissue Sarcoma of the Head and Neck

Soft Tissue Sarcoma of the Retroperitoneum

Soft Tissue Sarcoma of the Trunk and Extremities

Soft Tissue Sarcoma Unusual Histologies and Sites

Stomach

Testis

Ureter, Renal Pelvis

Uterus, Carcinoma and Carcinosarcoma

Uterus, Sarcoma

Vagina

Vulva

Studies:

REFLECTION is a multi-center, prospective, non-interventional, cohort study

The STRIVE Study: Development of a Blood Test for Early Detection of Multiple Cancer Types

This podcast is NOT medical advice. 

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