Semaglutide has recently been proven to induce significant weight loss in patients with obesity that is sustained for as long as the drug is given. Much attention has been given recently to Semaglutide in both scientific circles and in the media because of a landmark article in the New England Journal of Medicine addressing the impact of this medication in a large clinical trial. To explain this medication in detail and how and why it works I have Dr. David Yablonksy on this show. 

Topics Discussed Include:

How much weight are patients losing on Semaglutide?

Studies:

Once-Weekly Semaglutide in Adults with Overweight or Obesity

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use OZEMPIC® safely and effectively. See full prescribing information for OZEMPIC.

Semaglutide 2.4 mg for the Treatment of Obesity: Key Elements of the STEP Trials 1 to 5

Wegovy (semaglutide): a new weight loss drug for chronic weight management

The gut–brain axis: Identifying new therapeutic approaches for type 2 diabetes, obesity, and related disorders

Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity The STEP 3 Randomized Clinical Trial

More about Dr. Yablonsky:

Dr. David Yablonsky has been practicing medicine for over 20 years and is a board-certified internist. Dr. Yablonsky has experience in providing adults with help diagnosing a full range of medical issues including chronic disease management, primary care, hormone optimization, erectile dysfunction, weight loss and vitamin deficiencies. Dr. Yablonsky graduated with honors from Boston University prior to attending the Des Moines University College of Osteopathic Medicine. Upon completion of medical school, he went on to complete a three-year residency in Internal Medicine at the University of Rochester School of Medicine in Rochester, New York. His past leadership positions include Chief of Medicine, Internal Medicine Section Chief, Medical Director of Cardiopulmonary Rehabilitation and Chairman of Pharmacy and Therapeutics Committee at Grinnell Regional Medical Center in Grinnell, Iowa. Dr. Yablonsky’s focus is on disease prevention and health optimization. He has furthered his training by completing several conferences and courses in age management medicine including the elite training programs of Cenegenics, A4M, AMMG, and the International Peptide Society.

For questions about today's podcast you can contact Amy Stuttle at [email protected]

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