Sigma Nutrition Radio

SNR #256: Alex Leaf – Risks of High-Protein Diets?: Longevity, Gut Health & Microbiota


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Alex holds a master's degree in Nutrition from Bastyr University. He is a full-time researcher at Examine.com involved in updating the supplement database, editing ERD articles, and blogging about nutrition. Alex also teaches young minds about human nutrition and functional medicine at the University of Western States. He enjoys blending the scientific aspects of nutrition with the pragmatic realities of life to help others achieve their goals.

In This Episode We Discuss

  1. Potential controversies in how protein influences human health
  2. Hypothesis of protein restriction (and methionine restriction) benefitting longevity via impact on mTOR and AMPK
  3. Extrapolating animal data to humans: limits and conclusions
  4. Does protein restriction actually increase human lifespan?
  5. How do we balance the potential benefit of protein restriction with the known benefits of high-protein intakes for muscle mass and function?
  6. Are high-protein intakes detrimental for gut health and/or the gut microbiome?
  7. How other dietary components can mitigate the negative impacts of protein on gut health
  8. How cooking methods may influence the imapct of protein-rich foods on health
  9. Knowing the potential risks of a high-protein diet
  10. Cost:benefit analysis of protein intake

Support the podcast at: patreon.com/sigmanutrition

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