Welcome to the Gladden Longevity Podcast! Dr. Jeffrey Gladden and Steve Reiter are joined by Don Moxley, Director of Applied Science at Longevity Labs Inc., to explore optimizing life energy, longevity, and human performance. Don Moxley is the Director of Applied Science at Longevity Labs Inc. and the developer of HRV+ from Mode and Method. He is dedicated to helping people live vibrant, fulfilling lives at all ages, leveraging his background as an athlete, sports scientist, and instructor. Don simplifies complex science, focusing on autophagy and longevity. His work has positively impacted athletes, including Olympic medalists and national champions, by applying science to enhance well-being. Don shares insights on heart rate variability (HRV), Spermidine Life, NAD+ Life, and more. The conversation covers training's impact on athletic performance, outdoor activities' benefits, and wearable technology advancements. Don's passion for fitness and innovation shines through as he discusses sleep, holistic health, and embracing longevity. Tune in to discover the transformative power of living well beyond 120.

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Chapters Dr. Gladden shares how this is a fun and fascinating conversation. (1:i14) Dr. Gladden welcomes Don to the podcast. (3:26) All energy is eventually aerobic. (5:59) Dr. Gladden highlights that he does not build his own V02Max by doing zone 2 training. (9:30) How much blood your heart can pump per minute is so corrected with longevity. (12:05) Don says that the beauty of Zone 2 and Zone 3 is that there is no limit to how much you can do (16:02) Don talks about his earlier work with cannabis. (19:05) Don defines terpene. (22:43) Don shares about spermidine life products available. (23:10) Autophagy happens naturally with things like fasting and exercise. (29:00) Autophagy is a major part of wound healing. (34:00) Autophagy is not being taught in medical school at the moment. (38:25) Don explain low frequency and high frequency HRV states. (43:55) Every time a door closes, another opens. (46:58) Dr Gladden points out how people hold on to dogma, which leads to binary thinking, contrary to quantum thinking. (49:58) Don put a little HRV in his diet, putting him to sleep. (57:23) To improve your exercise, you should get a heart rate monitor. (59:57) One of the current challenges Don has is synthetic spermidine coming into the market. (1:01:54)

To know more about Don and his work: Email: [email protected] LinkedIn: https://www.linkedin.com/in/donmoxley/ Facebook: https://www.facebook.com/donmoxley/ Twitter/X: https://twitter.com/donmoxley?lang=en Websites: https://spermidinelife.us/ www.modemethod.com

Send your Qs for future episodes! Email: [email protected] Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

Gladden Longevity Podcast Disclosures

• Production & Independence

The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

• Medical Disclaimer

The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

Use of information from this podcast and any linked materials is at the listener's own risk.

• Podcast Guest Disclosures

Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

• Sponsorships & Affiliate Disclosures

To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

• Additional Note on Content Integrity

All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.