Niklas synthesizes insights after thinking about regulation & innovation by talking to experts and practitioners for more than 8 months.

Why are regulations important?

John Maynard Keynes observed that capital accumulation and technical improvements enabled economic growth.

Keynes calculated that with 2% growth per year, the economic pie increased by 7.5x in 100 years. If it would be 5%, it’s 130x our current level of wealth.

That would lead to an age of superabundance.

Regulations have a much larger impact on those than immediately obvious. They directly affect Keynes' factors of capital accumulation and technical improvements.

If we want to reach an age of superabundance, we need to look at our process for making rules that impact hundreds of millions of people

The 10 theses are:

(1) Our knowledge of the multi-layer effects of government regulation is comparable with medieval doctors' knowledge about the human body.

(2) It is an obfuscation to equate regulation with government regulation. There are many more ways for achieving the same effects.

(3) Our association of regulation with stability is influenced by pro-authority bias.

(4) Regulation mostly targets groups that are unpopular with the majority.

(5) Government regulation mostly follows as an overreaction to public events.

(6) We regulate seen consequences and disregard unseen consequences.

(7) In the absence of binding obligations, public officials have a herd mentality.

(8) Most business regulations fail because they don’t address the Safety Paradox.

(9) The main problem with regulation is the process of how we make decisions.

(10) Bad regulations are hard to get rid of (Machiavelli Effect).

Towards the end, Niklas discusses different solutions such as ethical exit, jurisdictional shopping, competition, and experimentation in governance.

Over the coming episodes of this podcast, we'll get more in-depth about solutions, entrepreneurs that achieved the impossible, what promising governance experiments are underway and how to achieve 100x growth for humanity.

Please send feedback and guest wishes to Niklas:

Discord: https://discord.gg/dwbNh7NK

Twitter: https://twitter.com/NiklasAnzinger

Email: [email protected]

Niklas speaks with Santiago Pinzon, the founder and CEO of ORKID.

ORKID aims to revolutionize healthcare in Latin America through autonomous drone delivery. In this episode, we talk about technological and regulatory challenges in the aviation industry, and how to unlock a future of rapid logistics.

Aviation is a fascinating industry that has developed high safety standards and technology that leads to extremely safe passenger flights.

However, we note something we call the "safety paradox". High safety standards lock in old technology to the detriment of experimentation with new technology, which could, inadvertently be even safe and have massive benefits.

The developed world has made it very hard for the commercial drone industry. The Federal Aviation Administration (FAA) applies the same standards to non-passenger drones as to passenger aircraft, i.e. drone delivery is regulated like an airline.

Standards developed by the International Civil Aviation Organization (ICAO) are not mandatory, but most countries abide by them because they lack the knowledge to assess new technologies or the willingness to try something new.

However, there are good news. A company named Zipline has been invited by a forward-thinking government administration in Rwanda to trial healthcare deliveries via drones. The success was amazing: reduced maternity mortality by 50-60%.

ORKID is close to a breakthrough with the regulator in Brazil, a country proud of its aviation industry, to start operations in Sao Paolo. Special jurisdictions like Prospera are similarly promising for drone adoption, and islands are a great use case.

The future of rapid logistics is coming, and ORKID is on the forefront!

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

Niklas talks with Joshua Scigala, the Co-Founder and CEO of TheStandard.io, which offers over-collateralized stablecoins backed by Gold, Bitcoin and Ethereum.

Josh and Niklas talk about the recent events surrounding the collapse of FTX, the crypto trading platform. Josh has been in the industry since 2010 and has seen many collapses and creative destruction over the years. He believes the industry has a way of overcoming failed experiments and bad ideas by writing better code.

Better code instead of laws and regulation is at the heart of the ethos of DeFi.

Secondly, we talk about stablecoins and Josh's mission to create a privatized and decentralized Gold Standard for the 21st century.

Stablecoins create access to the financial innovation of the crypto ecosystem while allowing a host of important everyday transactions. Unlike algorithmic stablecoins, TheStandard.io is backed by rare assets, i.e. Gold, Bitcoin and Ethereum.

The Standard aims to solve inflation by leveraging devaluation to work for savers, not against them. Besides leveraging rare assets, TheStandard.io also aims to innovate when it comes to decentralized governance through prediction markets.

The pace of financial innovation in DeFi is mesmerizing, but the industry is threatened on multiple fronts by bad PR and regulatory overreach. However, they survived multiple crises and came out stronger by building antifragile systems.

Join us on the mission to create a better, decentralized financial system for the Prospera Fintech & DeFi Summit 2022 (Nov 18-20).

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita VC Website: https://infinitavc.com/

Discord: https://discord.gg/Z4H6UjbubK

David K. Levine is an economist at the European University Institute and at Washington University in St. Louis. He is the author of Michele Boldrin of "Against Intellectual Monopoly", an empirical study of the economics of intellectual property (available for free here) that concludes that IP is not necessary for innovation and as a practical matter is damaging to growth, prosperity, and liberty.

IP law allegedly offers protection of innovation, most importantly in the form of patents and copyright. Most economists see IP protection as a "necessary evil". However, David believes they are in fact an unnecessary evil.

While IP laws do increase the reward for the innovator through a legally granted monopoly to produce and sell a unique product, they also have perverse effects such as making it costly and cumbersome to use other inventions, and they reward the inventor with better lawyers over the inventor with the better innovation.

So-called "patent trolls", for example, deliberately patent everything they can and sue other people to extract money. Surprisingly, many of the most famed inventors in history such as James Watts (steam engine) and the Wright Brothers (airplanes) turn out to be patent trolls. James Watts' predatory use of patent laws against his competitors had possibly delayed the Industrial Revolution by two decades.

David uses multiple examples from the music industry to the pharma industry to show that the alleged benefits of IP law are in fact empirically not demonstrated.

IP law is, therefore, a great example of a pernicious regulation that is holding back innovation not only in one but in many different industries across the board from media production, software, and financial markets all the way to pharma.

This episode offers deep insights into the history and mechanics of innovation. We learn about the so-called "lifecycle of innovation". Innovation typically starts with tinkerers and hobbyists, becomes a professional industry, and develops wide use of patents only late in its development to sustain the privilege of incumbents.

It shows that we need to develop a much better understanding of innovation as a process that requires permissionless tinkering.

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Website: https://infinitavc,com/

Discord: https://discord.gg/Z4H6UjbubK

Niklas speaks with Caroline Cochran, the COO and co-founder of Oklo, joined by special guest Mac Davis, the CEO of Minicircle.

Oklo is revolutionizing nuclear energy to create a clean energy future.

Nuclear energy is probably the best example of a stranded technology. It has the potential to give us a low-to-no-cost, low-to-no-carbon future economy - but it is held back by industry stagnation, political obstacles and regulatory strangulation.

In this episode, we'll learn about Oklo and Caroline's mission, and how so-called "powerhouses", micro-scale advanced fission power plants that are orders of magnitude safer than old nuclear power plans, can disrupt the energy industry.

The safety of these micro-plants is by design, using metal fuels. If the fuel expands through heat, the metal expands to shut down the reaction.

Caroline explains the process of convincing the Nuclear Regulatory Commission (NRC), a regulatory agency that has not licensed a single commercial nuclear power plant from application to start of operations since its beginnings in 1974.

While the process can be slow and expensive, Caroline also observes that their path has been one of much faster iteration and that nuclear is increasingly on a path to greater acceptance.

Oklo is on track to build the first NRC-licensed nuclear reactors, paving the way for a nuclear revival to produce cheap and clean electricity that is advancing humanity in the fight again climate change and accelerating technological progress.

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

J. Storrs Hall or "Josh" is an independent researcher and author.

He was the founding Chief Scientist of Nanorex, which is developing a CAD system for nanomechanical engineering.

His research interests include molecular nanotechnology and the design of useful macroscopic machines using the capabilities of molecular manufacturing. His background is in computer science, particularly parallel processor architectures, artificial intelligence, particularly agoric and genetic algorithms.

This episode is filled with techno-optimist verve.

Josh wrote an epic book called "Where is My Flying Car - A Memoir of Future Past".

The book is the subject of the conversation, for which we're joined by Trey Goff - the CMO of the startup city Prospera, who sees the book as his ideology.

The book starts as an examination of the technical limitations of building flying cars and evolves into an investigation of the scientific, technological, and social roots of the economic stagnation that started in the 1970s.

The period from 1880 to 1940 brought major technological advances: electricity, electric lights, powerful motors, automobiles, airplanes, household appliances, the telephone, indoor plumbing, pharmaceuticals, mass production, the typewriter, the tape recorder, the phonograph, and radio, and television.

Today, in contrast, apart from the seemingly magical internet, life in broad material terms isn’t so different from what it was in 1953.

Scholars like Tyler Cowen and Robert J. Gordon spoke of "The Great Stagnation".

Josh has explosive insights into the history of regulation and technology that show how different our lives could be.

At the center of losing out on major new innovations in the world of atoms is nuclear energy. The world not producing enough clean energy at scale to advance in energy-intensive areas such as nanotechnology, air & space travel, and advanced materials.

We learn that flying cars are a real possibility, even right now.

It's just due to policy changes and a culture of "safetyism" that sometimes deliberately, sometimes inadvertently holds back progress.

Is humanity ending up like the "Eloi" in H.G. Well's novel "The Time Machine": lazy, stupid and timid due to the coddling effect of advanced technology?

Josh says "No"! Humanity can do better.

Human ingenuity is endless, and we can invigorate our passions to reach to the frontiers into new and hostile environments, master the elements through the scientific method and engineer our environments for human flourishing.

This episode is a rallying cry to build a better future now!

J. Storrs Hall's website: https://autogeny.org/

Prospera's website: https://prospera.hn/

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Fund Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

Dusan is the Founder and CEO of the AmityAge Academy, a Bitcoin Education Center based in the startup city of Prospera on the island of Roatan, Honduras.

The mission of the academy is to accelerate bitcoinization.

Dusan and Niklas share a special history.

Dusan heard about the paradise island of Roatan, Honduras from a friend. While he was visiting in April, he heard about the "Build Prospera Summit 2022".

The conference was organized as an "unconference", so it was very open for every participant to engage and bring their ideas.

On the last day, we had a pitch competition. Dusan spontaneously pitched a long-held idea: a Bitcoin Education Center.

Dusan gave a fantastic presentation, where he talked about his goal to "educate 100m people about bitcoin by 2030".

After the talk, Prospera CEO Erick A. Brimen told Dusan: "Come with me, I show you a place where you can do it."

The rest is history.

In this episode, you'll hear more about Dusan's journey to becoming a Bitcoin educator, how he teaches children bout Bitcoin, living in and working with the communities in Roatan, and why Dusan is a Bitcoin Maximalist.

Dusan and Niklas debate the maximalist thesis, talking about competition vs. efficiency when it comes to creating a store of value, the risk of default of governments & fiat currencies vs. Bitcoin, and the path to broad adoption.

The AmityAge Academy will have its grand opening on November 18, in the wake of the Prospera Fintech & DeFi Summit 2022 (Nov 18-20). Join us on this dreamy island to build the future of money together: https://infinitafund.com/fintech2022

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Fund Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

Savva is the Founder and CEO of Crowd Funded Cures, a New Zealand-based charity and Open Source Pharma De-Sci Organisation.

Savva and Niklas talk about the pharmaceutical market, and how the interplay of clinical trials and the patent system disincentivize pharma companies from producing widely available drugs that could significantly improve people's lives.

This is another deep dive into one of the largest markets in the world, healthcare, and into the possible future using blockchain technology to disrupt it.

Savva describes three core concepts: a Health Impact Fund, Pay-For-Success Contracts and intellectual property (IP) NFTs (non-fungible tokens).

Together, these legal and technological innovations can create the right incentives and create a scalable business model to fund clinical trials for off-patent, generic drugs such as ketamine to treat depression, which is only $2 a dose compared to expensive patented drugs such as esketamine for over $850 a dose.

This is important because the pharmaceutical industry is disincentivized from conducting clinical trials, if they can't enforce a monopoly price. Because people can buy generic drugs cheaply from multiple sources, they can't create a business model by charging a monopoly price and suing other companies. This is why we need new "pay-for-success" contracts to fix this market failure under the traditional IP system.

There are over 7500 off-patent drugs and 50,000 supplements that could be repurposed to treat new diseases at up to 1/100th of the cost and 5-10x faster than new patented drugs.

Savva offers deep insights into the broken incentives of the pharmaceutical system, but he is describing key innovations enabled by blockchain technology that has the potential to create an open-source, decentralized science ecosystem.

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Fund Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

Niklas speaks with Silicon Valley-based serial entrepreneur John Chisholm.

Over the last 35 years, John has founded, grown, or sold four companies in Silicon Valley, including Decisive Technology, now part of Google; and CustomerSat, now part of FocusVision. He has served as president and chair of the worldwide MIT Alumni Association, and as trustee of MIT and the Santa Fe Institute. Today, John is CEO of John Chisholm Ventures, a startup advisory, and angel investment firm. He is the author of “Unleash Your Inner Company: 10 Steps to Discover, Launch, and Scale Your Ideal Business.”

Among much else, Niklas & John explore the thesis of entrepreneurship as a stranded technology. Technology can be stranded by failing to attract sufficient investment to compete, such as automobiles propelled by steam as compared to internal combustion engines in the early 20th century; or by being superseded by other technologies, such as fax has been replaced by email and messaging; or by regulation, such as nuclear energy today.

Similarly, entrepreneurship is increasingly being stranded. Across the United States, entrepreneurship is on the decline. According to the Kauffman Foundation, as a percentage of all businesses, new firms have dropped from 16% in 1977 to fewer than 8% in 2010. This encompasses all new businesses – sole proprietorships, retail stores, service providers, restaurants, consultants – not just high-tech.

In this session with John Chisholm, we’ll see how a combination of factors, both external & regulatory, on the one hand, and internal & psychological on the other, is holding back entrepreneurs today. John offers recommendations both for aspiring entrepreneurs on how to discover, launch and scale a business ideal for them, and also for lawmakers and regulators on how to make their jurisdictions more economically resilient, humane, and friendly to startups and innovation, via such techniques as localism, sunset clauses, and special economic zones.

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Fund Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK

Niklas speaks with Zina Sarif, the Founder and Managing Director of Yendou, a company on a mission to accelerate clinical research and make it universally accessible to patients, clinicians, and scientists.

Zina starts by talking about her familial experiences with cancer during her upbringing in Morocco, and how it motivated her to dedicate her life to combating cancer.

During her career as.a cancer scientist in Germany, Zina experienced the inefficiencies and bureaucratic obstacles to bringing solutions from the science to market.

It takes 12 years and $800m in cost to bring a new treatment to market, and the shortened patent life cycle pushes for non-patient-centric incentives.

"We are currently not winning the war against cancer," so Zina.

However, Zina has identified hope for patients.

Clinical trials contain the most innovative treatments for cancer, and they typically take place in large hospitals with great infrastructure and care options for patients,

Yet only 8% of cancer patients globally are participating in clinical trials, and it takes 18 months to get access - often too long to have a chance at survival

With Yendou, Zina aims to reduce the time to access new treatments from 18 to 4 months and enable more patients to access them.

But this is only the beginning. Long-term, Yendou aims to reduce the time for clinical trials from 12 to 7 years and reduce costs from $800m to $300m.

We learn in the conversation how medical innovation in oncology is held back by a Kafkaesque bureaucracy, a frustrating reality that takes a toll on innovators.

Yet, Zina is bent on overcoming seemingly insurmountable obstacles and encouraging hope that the war against cancer is not over.

Niklas on Twitter: https://twitter.com/NiklasAnzinger

Infinita Fund Website: https://infinitafund.com/

Discord: https://discord.gg/Z4H6UjbubK