Molly Webster, producer and reporter at WNYC's Radiolab, and Dr. Li-Huei Tsai, picower professor of neuroscience, director of MIT’s Picower Institute for Learning and Memory, and senior author of the study in Nature, "Gamma frequency entrainment attenuates amyloid load and modifies microglia", discuss Dr. Li-Heui's new research on the use of flashing LED lights to ward off Alzheimer's in mice.

Dr. Li-Huei Tsai: If a sense is directed at you with a rhythm, then your neurons can be trained to fire at a similar frequency.

A caller wonders about the ethical concerns of doing research on Alzheimer's patients, some of whom may not fully understand consent

On the 75th anniversary of the attack on Pearl Harbor, Steven Gillon, professor of history at the University of Oklahoma and resident historian for the History Channel and author of Pearl Harbor: FDR Leads the Nation Into War (Basic Books, 2011), talks about the ensuing 24 hours and takes calls from WWII veterans. Also, hear a clip of WNYC's original reporting on Pearl Harbor; WNYC was the first radio station to report on the attack.

For our weekly Ask The Mayor segment, Bill de Blasio, mayor of New York City, takes calls from listeners and discusses this week in NYC, including the city's conflict over who will pay for protecting Trump Tower, homelessness, water bill policy, and more.

"It's only round one," BdB tells @BrianLehrer re limited proposed federal reimbursement to NYC for protecting Trump

"Any act of violence, any threat, any hate speech, we want people to report it immediately," de Blasio tells @BrianLehrer

"Maybe you should ask for federal protection for Muslims," @BrianLehrer says to Mayor de Blasio, amid spike in hate crimes.

"This city never recovered from the cancellation of the advantage program." - @BilldeBlasio on NYC's homeless population

Dina Gilio-Whitaker, Colville Confederated Tribes columnist at Indian Country Today Media Network, research associate and associate scholar at the Center for World Indigenous Studies, and Roxanne Dunbar-Ortiz, professor emeritus of Native American studies at California State University and native of rural Oklahoma, co-authored the new book “All the Real Indians Died Off": And 20 Other Myths About Native Americans(Beacon Press, 2016). They discuss the history and current state of indigenous culture and reflect on the recent developments in Standing Rock.

Miriam Laugesen, associate professor in the department of Health Policy and Management at the Mailman School of Public Health, Columbia University and the author of Fixing Medical Prices: How Physicians Are Paid (Harvard University Press, 2016), explores the way reimbursement rates for doctors are set by their professional organizations and what that means for overall spending and care.

Cokie Roberts, NPR commentator and the author of Ladies of Liberty: The Women Who Shaped Our Nation, talks with Brian about her book which explores the influence of America's foremothers on our nascent democracy.

What faults did the Trump candidacy expose in the media landscape?  How are social media and new technology exacerbating polarization (and fake news)? Bob Garfield, co-host of WNYC's On the Media and the host of "The Genius Dialogues" podcast for Audible, examines the most pressing concerns about journalism in the wake of Trump’s election.

Here is On The Media's Breaking News Consumer's Handbook for spotting and avoiding fake news:

@BrianLehrer @Bobosphere Why do we refer to most of these stories as "fake news" instead of "propaganda"? Is there a difference?

@BrianLehrer Another sign of fake news: " you won't see this on mainstream media" #headsup

wasn't liberals saying "content should be free" it was one WIRED EIC. It's the tech industry that wanted it free @BrianLehrer

@BrianLehrer "Fake News" is now becoming a label used by alt-right to discredit left-leaning publications

@brianlehrer When will journalism have a clearing house like Underwriters Lab for websites?

@BrianLehrer @Bobosphere giving FB the power the moderate what is “true" or “false” is the wrong idea. we need media education. on FB!

@BrianLehrer @Bobosphere I'm wondering if only those beyond the paywall are going to get "real" reporting going forward. (1/2)

@BrianLehrer @Bobosphere & if programmatic buying/social distribution where platform wins make responsible reporting a scarce, luxury good

@KylieSobel @BrianLehrer @Bobosphere Most consumers aren’t going to the original reporting anyway. But we need good 2nd-layer distribution.

Editor's note: Police say Yasmin Seweid, the woman mentioned in this story who claimed she was harassed by three men on a Manhattan subway for being Muslim, fabricated her story. She has since been arrested on charges of obstructing governmental administration and filing a false report of an incident.

A spate of hate-crimes, many of them against Muslims, have occurred in the month following the election of Donald Trump. Just yesterday, in Manhattan, an MTA worker wearing a hijab was pushed down the stairs at Grand Central Terminal. WNYC's Arun Venugopal talks to listeners about what they can do if they experience harassment or witness a hate-crime in progress.

@BrianLehrer @arunNYC I use my mommy voice and scold them. Works every time.

Marc Levinson, former finance and economics editor at The Economist and the author of An Extraordinary Time: The End of the Postwar Boom and the Return of the Ordinary Economy (Basic Books, 2016), argues that the prosperity and growth experienced in the years after World War II were an aberration, and that we're now heading back to economic reality.

Trump has recently incited controversy by breaking a decades-long official silence between American and Taiwanese heads of state. He also told Pakistan's Prime Minister, "You are a terrific guy. You are doing amazing work which is visible in every way." Fred Kaplan, Slate's War Stories columnist and the author of Dark Territory: The Secret History of Cyber War (Simon & Schuster, 2016), discusses these recent conversations with foreign leaders and what kind of foreign policy Trump might (or might not) be planning.

"In many places in the world, there r things that r known as 'strategic ambiguities.' " @fmkaplan, to @BrianLehrer, re Trump&foreign policy

@fmkaplan @BrianLehrer The President of United States CAN NOT play the role of the"JOKER"!People real life matters,wordly real life matters!

@fmkaplan: Petraeus being a general might work against his likelihood of being picked by Trump for Secretary of State