Jon Cohen, senior correspondent with Science, reports on how countries that suffer high rates of HIV/AIDS are coping now that USAID funding has dried up, and how local governments, especially in places like Lesotho, are attempting to figure out solutions. Plus, Wafaa El-Sadr, MD, Columbia University professor of epidemiology and medicine and director of ICAP, a global health center at the school of public health, discusses ICAP's work in implementing PEPFAR (the President’s Emergency Plan for AIDs Relief) in sub-Saharan Africa, and discusses the future of PEPFAR under the Trump administration.

Marisa Donnelly, PhD, New York correspondent for Your Local Epidemiologist, talks about the various public health policies the mayoral candidates support, and what the mayor can do about public health more broadly.

Julie Tighe, president of New York League of Conservation Voters, and Keanu Arpels-Josiah, climate justice organizer with Fridays for Future NYC, talks about the mayoral candidates' positions on climate change and the environment.

Errol Louis, political anchor of Spectrum NY1 News, host of Inside City Hall and The Big Deal with Errol Louis, New York Magazine columnist and host of the podcast You Decide, offers analysis of the mayoral primary debate, and talks about the latest news from the campaign trail as early voting is underway.

Robert Macfarlane, a fellow at the University of Cambridge and the author of several books, including Underland and his new one, Is a River Alive? (W. W. Norton & Company, 2025), talks about the new book that questions how we treat rivers through the stories of rivers in Ecuador, India and Canada.

Susan Glasser, staff writer at The New Yorker and author of a weekly column on life in Washington, and the host of the Political Scene podcast, talks about the latest national political news, including the latest on Los Angeles, President Trump's military parade, the "No More Kings" protests and the politically-motivated shooting of lawmakers in Minnesota.

David Brand, housing reporter for WNYC and Gothamist, offers analysis of the housing plans the mayoral candidates discussed in last week's Spectrum News NY1 debate.

Three of our favorite segments from the week, in case you missed them.

New Jersey’s Gubernatorial Primary Results (First) | The Gay Restaurants That Nurtured LGBTQ Americans (Starts at 45:00) | Mapping the Stars (Starts at 59:00)

If you don't subscribe to the Brian Lehrer Show on iTunes, you can do that here.

An extended excerpt from Thursday's debate between the leading Democrats running for the mayoral nomination. In this last section of the debate, the candidates discuss traffic and pedestrian safety.

An extended excerpt from Thursday's debate between the leading Democrats running for the mayoral nomination. In the first part of this clip, we hear the candidates discuss Andrew Cuomo's sexual harassment scandal, and then we hear them addressing their approaches to public safety.